Roles of perirhinal and posterior piriform cortices in control and generation of seizures: A microinfusion study in rats exposed to soman

Identification of critical receptors in seizure controlling brain regions may facilitate the development of more efficacious pharmacological therapies against nerve agent intoxication. In the present study, a number of drugs with anticonvulsant potency were microinfused into the perirhinal cortex (P...

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Veröffentlicht in:	Neurotoxicology (Park Forest South) 2010, Vol.31 (1), p.147-153
Hauptverfasser:	Myhrer, Trond, Enger, Siri, Aas, Pål
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors (muscarinic) Animals Anticonvulsant effects Anticonvulsants - pharmacology Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Cerebral Cortex - drug effects Cerebral Cortex - physiology Chemical and industrial products toxicology. Toxic occupational diseases Disease Models, Animal Drugs Electroencephalography - methods GABA Agonists - adverse effects Gas, fumes Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Male Medical sciences Microinfusions Muscarinic Antagonists - adverse effects Muscimol - adverse effects Nervous system (semeiology, syndromes) Neurology Neuropharmacology Perirhinal cortex Pharmacology. Drug treatments Posterior piriform cortex Procyclidine - therapeutic use Quinoxalines - pharmacology Rats Rats, Wistar Scopolamine Hydrobromide - adverse effects Seizures Seizures - chemically induced Seizures - drug therapy Seizures - pathology Soman Statistics, Nonparametric Toxicology
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