central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription

The cell cycle-dependent element (CDE) and the cell cycle genes homology region (CHR) control the transcription of genes with maximum expression in G₂ phase and in mitosis. Promoters of these genes are repressed by proteins binding to CDE/CHR elements in G₀ and G₁ phases. Relief from repression begi...

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Veröffentlicht in:	The FEBS journal 2010-02, Vol.277 (4), p.877-893
Hauptverfasser:	Müller, Gerd A, Engeland, Kurt
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals binding proteins Binding sites Biochemistry Cell cycle cell cycle genes homology region (CHR) cell cycle-dependent element (CDE) cyclins DREAM complex E2F Gene expression Gene Expression Regulation genes Genes, cdc - physiology histones Humans interphase mitosis Models, Biological nucleotides promoter regions Promoter Regions, Genetic - genetics Proteins transcription (genetics) transcription factors
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