Rate of metabolism of norethisterone in women from different populations
The rate of metabolism of orally administered norethisterone was compared in fourteen centres by measuring plasma levels of the steroid by radioimmunoassay at varying times after oral administration of a 1 mg dose. The inter-centre differences were of the same order as the intra-centre differences....
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Veröffentlicht in: | Contraception (Stoneham) 1979, Vol.19 (1), p.39-45 |
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creator | Fotherby, K. Shrimanker, K. Abdel-Rahman, H.A. Toppozada, H.K. de Souza, J.C. Coutinho, E.M. Koetsawang, S. Nukulkarn, P. Sheth, U.K. Mapa, M.K. Gopalan, S. Plunkett, E.R. Brenner, P.F. Hickey, M.V. Grech, E.S. Lichtenberg, R. Gual, C. Molina, R. Gomez-Rogers, C. Kwon, E. Kim, S.W. Chan, T. Ratnam, S.S. Landgren, B.M. Shearman, R.P. |
description | The rate of metabolism of orally administered norethisterone was compared in fourteen centres by measuring plasma levels of the steroid by radioimmunoassay at varying times after oral administration of a 1 mg dose. The inter-centre differences were of the same order as the intra-centre differences. Variations in metabolism appeared not to be due to variations in body size. |
doi_str_mv | 10.1016/S0010-7824(79)80007-4 |
format | Article |
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The inter-centre differences were of the same order as the intra-centre differences. Variations in metabolism appeared not to be due to variations in body size.</description><identifier>ISSN: 0010-7824</identifier><identifier>EISSN: 1879-0518</identifier><identifier>DOI: 10.1016/S0010-7824(79)80007-4</identifier><identifier>PMID: 428223</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Female ; Half-Life ; Humans ; Norethindrone - blood ; Norethindrone - metabolism</subject><ispartof>Contraception (Stoneham), 1979, Vol.19 (1), p.39-45</ispartof><rights>1979 Geron-X, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-43ffc83a282705284d9aab95d89313a54210ad81c87cd97b62379b1b0931e6a3</citedby><cites>FETCH-LOGICAL-c406t-43ffc83a282705284d9aab95d89313a54210ad81c87cd97b62379b1b0931e6a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0010-7824(79)80007-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/428223$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fotherby, K.</creatorcontrib><creatorcontrib>Shrimanker, K.</creatorcontrib><creatorcontrib>Abdel-Rahman, H.A.</creatorcontrib><creatorcontrib>Toppozada, H.K.</creatorcontrib><creatorcontrib>de Souza, J.C.</creatorcontrib><creatorcontrib>Coutinho, E.M.</creatorcontrib><creatorcontrib>Koetsawang, S.</creatorcontrib><creatorcontrib>Nukulkarn, P.</creatorcontrib><creatorcontrib>Sheth, U.K.</creatorcontrib><creatorcontrib>Mapa, M.K.</creatorcontrib><creatorcontrib>Gopalan, S.</creatorcontrib><creatorcontrib>Plunkett, E.R.</creatorcontrib><creatorcontrib>Brenner, P.F.</creatorcontrib><creatorcontrib>Hickey, M.V.</creatorcontrib><creatorcontrib>Grech, E.S.</creatorcontrib><creatorcontrib>Lichtenberg, R.</creatorcontrib><creatorcontrib>Gual, C.</creatorcontrib><creatorcontrib>Molina, R.</creatorcontrib><creatorcontrib>Gomez-Rogers, C.</creatorcontrib><creatorcontrib>Kwon, E.</creatorcontrib><creatorcontrib>Kim, S.W.</creatorcontrib><creatorcontrib>Chan, T.</creatorcontrib><creatorcontrib>Ratnam, S.S.</creatorcontrib><creatorcontrib>Landgren, B.M.</creatorcontrib><creatorcontrib>Shearman, R.P.</creatorcontrib><title>Rate of metabolism of norethisterone in women from different populations</title><title>Contraception (Stoneham)</title><addtitle>Contraception</addtitle><description>The rate of metabolism of orally administered norethisterone was compared in fourteen centres by measuring plasma levels of the steroid by radioimmunoassay at varying times after oral administration of a 1 mg dose. The inter-centre differences were of the same order as the intra-centre differences. Variations in metabolism appeared not to be due to variations in body size.</description><subject>Adult</subject><subject>Female</subject><subject>Half-Life</subject><subject>Humans</subject><subject>Norethindrone - blood</subject><subject>Norethindrone - metabolism</subject><issn>0010-7824</issn><issn>1879-0518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE9LxDAQxYP4b139Bgo9iR6qSZs2yUlkUVdYEHTvIU2mGGmbNUkVv73tdvHqaRjee_OYH0IXBN8QTMrbN4wJThnP6BUT1xxjzFK6h2aEM5HigvB9NPuzHKOTED5GjyjYETqkGc-yfIaWrypC4uqkhagq19jQjlvnPMR3GyJ410Fiu-TbtdAltXdtYmxdg4cuJhu36RsVrevCKTqoVRPgbDfnaP34sF4s09XL0_PifpVqisuY0ryuNc_VUM9wkXFqhFKVKAwXOclVQTOCleFEc6aNYFWZ5UxUpMKDDKXK5-hyOrvx7rOHEGVrg4amUR24PkhGac5pVg7GYjJq70LwUMuNt63yP5JgOfKTW35yhCOZkFt-kg65811BX7Vg_lITsEG-m2QYfvyy4GXQFjoNxnrQURpn_yn4BbL8fzQ</recordid><startdate>1979</startdate><enddate>1979</enddate><creator>Fotherby, K.</creator><creator>Shrimanker, K.</creator><creator>Abdel-Rahman, H.A.</creator><creator>Toppozada, H.K.</creator><creator>de Souza, J.C.</creator><creator>Coutinho, E.M.</creator><creator>Koetsawang, S.</creator><creator>Nukulkarn, P.</creator><creator>Sheth, U.K.</creator><creator>Mapa, M.K.</creator><creator>Gopalan, S.</creator><creator>Plunkett, E.R.</creator><creator>Brenner, P.F.</creator><creator>Hickey, M.V.</creator><creator>Grech, E.S.</creator><creator>Lichtenberg, R.</creator><creator>Gual, C.</creator><creator>Molina, R.</creator><creator>Gomez-Rogers, C.</creator><creator>Kwon, E.</creator><creator>Kim, S.W.</creator><creator>Chan, T.</creator><creator>Ratnam, S.S.</creator><creator>Landgren, B.M.</creator><creator>Shearman, R.P.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1979</creationdate><title>Rate of metabolism of norethisterone in women from different populations</title><author>Fotherby, K. ; Shrimanker, K. ; Abdel-Rahman, H.A. ; Toppozada, H.K. ; de Souza, J.C. ; Coutinho, E.M. ; Koetsawang, S. ; Nukulkarn, P. ; Sheth, U.K. ; Mapa, M.K. ; Gopalan, S. ; Plunkett, E.R. ; Brenner, P.F. ; Hickey, M.V. ; Grech, E.S. ; Lichtenberg, R. ; Gual, C. ; Molina, R. ; Gomez-Rogers, C. ; Kwon, E. ; Kim, S.W. ; Chan, T. ; Ratnam, S.S. ; Landgren, B.M. ; Shearman, R.P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-43ffc83a282705284d9aab95d89313a54210ad81c87cd97b62379b1b0931e6a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Adult</topic><topic>Female</topic><topic>Half-Life</topic><topic>Humans</topic><topic>Norethindrone - blood</topic><topic>Norethindrone - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fotherby, K.</creatorcontrib><creatorcontrib>Shrimanker, K.</creatorcontrib><creatorcontrib>Abdel-Rahman, H.A.</creatorcontrib><creatorcontrib>Toppozada, H.K.</creatorcontrib><creatorcontrib>de Souza, J.C.</creatorcontrib><creatorcontrib>Coutinho, E.M.</creatorcontrib><creatorcontrib>Koetsawang, S.</creatorcontrib><creatorcontrib>Nukulkarn, P.</creatorcontrib><creatorcontrib>Sheth, U.K.</creatorcontrib><creatorcontrib>Mapa, M.K.</creatorcontrib><creatorcontrib>Gopalan, S.</creatorcontrib><creatorcontrib>Plunkett, E.R.</creatorcontrib><creatorcontrib>Brenner, P.F.</creatorcontrib><creatorcontrib>Hickey, M.V.</creatorcontrib><creatorcontrib>Grech, E.S.</creatorcontrib><creatorcontrib>Lichtenberg, R.</creatorcontrib><creatorcontrib>Gual, C.</creatorcontrib><creatorcontrib>Molina, R.</creatorcontrib><creatorcontrib>Gomez-Rogers, C.</creatorcontrib><creatorcontrib>Kwon, E.</creatorcontrib><creatorcontrib>Kim, S.W.</creatorcontrib><creatorcontrib>Chan, T.</creatorcontrib><creatorcontrib>Ratnam, S.S.</creatorcontrib><creatorcontrib>Landgren, B.M.</creatorcontrib><creatorcontrib>Shearman, R.P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Contraception (Stoneham)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fotherby, K.</au><au>Shrimanker, K.</au><au>Abdel-Rahman, H.A.</au><au>Toppozada, H.K.</au><au>de Souza, J.C.</au><au>Coutinho, E.M.</au><au>Koetsawang, S.</au><au>Nukulkarn, P.</au><au>Sheth, U.K.</au><au>Mapa, M.K.</au><au>Gopalan, S.</au><au>Plunkett, E.R.</au><au>Brenner, P.F.</au><au>Hickey, M.V.</au><au>Grech, E.S.</au><au>Lichtenberg, R.</au><au>Gual, C.</au><au>Molina, R.</au><au>Gomez-Rogers, C.</au><au>Kwon, E.</au><au>Kim, S.W.</au><au>Chan, T.</au><au>Ratnam, S.S.</au><au>Landgren, B.M.</au><au>Shearman, R.P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rate of metabolism of norethisterone in women from different populations</atitle><jtitle>Contraception (Stoneham)</jtitle><addtitle>Contraception</addtitle><date>1979</date><risdate>1979</risdate><volume>19</volume><issue>1</issue><spage>39</spage><epage>45</epage><pages>39-45</pages><issn>0010-7824</issn><eissn>1879-0518</eissn><abstract>The rate of metabolism of orally administered norethisterone was compared in fourteen centres by measuring plasma levels of the steroid by radioimmunoassay at varying times after oral administration of a 1 mg dose. 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subjects | Adult Female Half-Life Humans Norethindrone - blood Norethindrone - metabolism |
title | Rate of metabolism of norethisterone in women from different populations |
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