Malignant potential of chronic ulcerative colitis. Preliminary report
Prior studies confirm the increased incidence of carcinoma of the colon in chronic ulcerative colitis. The authors reviewed clinical and histologic data retrospectively in 23 patients with colon carcinoma and chronic ulcerative colitis. Twenty-two of these patients had dysplasia of colonic epitheliu...
Gespeichert in:
| Veröffentlicht in: | Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1979-01, Vol.76 (1), p.1-5 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 5 |
|---|---|
| container_issue | 1 |
| container_start_page | 1 |
| container_title | Gastroenterology (New York, N.Y. 1943) |
| container_volume | 76 |
| creator | Nugent, F W Haggit, R C Colcher, H Kutteruf, G C |
| description | Prior studies confirm the increased incidence of carcinoma of the colon in chronic ulcerative colitis. The authors reviewed clinical and histologic data retrospectively in 23 patients with colon carcinoma and chronic ulcerative colitis. Twenty-two of these patients had dysplasia of colonic epithelium remote from the cancer. The authors prospectively reviewed clinical data and rectal and colonoscopic biopsy specimens on 36 patients with chronic ulcerative colitis, 12 with Crohn's colitis, and 12 with miscellaneous disorders. Eight patients with chronic ulcerative colitis had dysplasia; 6 have had colectomy, and 2 of these had carcinoma. No patient without chronic ulcerative colitis had dysplasia. Patients with chronic ulcerative colitis should have periodic rectal and colonoscopic biopsies, and those with moderate to marked dysplasia require colectomy because of the increased risk of colon carcinoma. |
| doi_str_mv | 10.1016/S0016-5085(79)80119-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_74437541</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>74437541</sourcerecordid><originalsourceid>FETCH-LOGICAL-p205t-dcf5cf266fad8b0a7d45b80134157eb92802f310019e93b210a80fbadfbc791d3</originalsourceid><addsrcrecordid>eNo9j01LxDAYhHPwa139Bwo9iR66vmmaTXKUZf2AFQX1XJI00Uja1CQV9t9b2MXLDAzD8AxClxgWGPDy9g0mLSlwes3EDQeMRUkP0Ow_PkGnKX0DgCAcH6MjRjkmMEPrZ-ndZy_7XAwhmz476YtgC_0VQ-90MXptoszu1xQ6eJddWhSv0XjXuV7GbRHNEGI-Q4dW-mTO9z5HH_fr99VjuXl5eFrdbcqhAprLVluqbbVcWtlyBZK1NVUTLKkxZUaJikNlCZ6ghRFEVRgkB6tka5VmArdkjq52u0MMP6NJuelc0sZ72ZswpobVNWG0xlPxYl8cVWfaZoium3Cb3W3yB9X9WVM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>74437541</pqid></control><display><type>article</type><title>Malignant potential of chronic ulcerative colitis. Preliminary report</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><source>Alma/SFX Local Collection</source><creator>Nugent, F W ; Haggit, R C ; Colcher, H ; Kutteruf, G C</creator><creatorcontrib>Nugent, F W ; Haggit, R C ; Colcher, H ; Kutteruf, G C</creatorcontrib><description>Prior studies confirm the increased incidence of carcinoma of the colon in chronic ulcerative colitis. The authors reviewed clinical and histologic data retrospectively in 23 patients with colon carcinoma and chronic ulcerative colitis. Twenty-two of these patients had dysplasia of colonic epithelium remote from the cancer. The authors prospectively reviewed clinical data and rectal and colonoscopic biopsy specimens on 36 patients with chronic ulcerative colitis, 12 with Crohn's colitis, and 12 with miscellaneous disorders. Eight patients with chronic ulcerative colitis had dysplasia; 6 have had colectomy, and 2 of these had carcinoma. No patient without chronic ulcerative colitis had dysplasia. Patients with chronic ulcerative colitis should have periodic rectal and colonoscopic biopsies, and those with moderate to marked dysplasia require colectomy because of the increased risk of colon carcinoma.</description><identifier>ISSN: 0016-5085</identifier><identifier>DOI: 10.1016/S0016-5085(79)80119-5</identifier><identifier>PMID: 758130</identifier><language>eng</language><publisher>United States</publisher><subject>Adolescent ; Adult ; Aged ; Biopsy ; Child ; Colectomy ; Colitis, Ulcerative - complications ; Colitis, Ulcerative - pathology ; Colon - pathology ; Colonic Neoplasms - etiology ; Colonic Neoplasms - pathology ; Humans ; Intestinal Mucosa - pathology ; Middle Aged ; Precancerous Conditions - pathology ; Retrospective Studies ; Risk ; Time Factors</subject><ispartof>Gastroenterology (New York, N.Y. 1943), 1979-01, Vol.76 (1), p.1-5</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/758130$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nugent, F W</creatorcontrib><creatorcontrib>Haggit, R C</creatorcontrib><creatorcontrib>Colcher, H</creatorcontrib><creatorcontrib>Kutteruf, G C</creatorcontrib><title>Malignant potential of chronic ulcerative colitis. Preliminary report</title><title>Gastroenterology (New York, N.Y. 1943)</title><addtitle>Gastroenterology</addtitle><description>Prior studies confirm the increased incidence of carcinoma of the colon in chronic ulcerative colitis. The authors reviewed clinical and histologic data retrospectively in 23 patients with colon carcinoma and chronic ulcerative colitis. Twenty-two of these patients had dysplasia of colonic epithelium remote from the cancer. The authors prospectively reviewed clinical data and rectal and colonoscopic biopsy specimens on 36 patients with chronic ulcerative colitis, 12 with Crohn's colitis, and 12 with miscellaneous disorders. Eight patients with chronic ulcerative colitis had dysplasia; 6 have had colectomy, and 2 of these had carcinoma. No patient without chronic ulcerative colitis had dysplasia. Patients with chronic ulcerative colitis should have periodic rectal and colonoscopic biopsies, and those with moderate to marked dysplasia require colectomy because of the increased risk of colon carcinoma.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biopsy</subject><subject>Child</subject><subject>Colectomy</subject><subject>Colitis, Ulcerative - complications</subject><subject>Colitis, Ulcerative - pathology</subject><subject>Colon - pathology</subject><subject>Colonic Neoplasms - etiology</subject><subject>Colonic Neoplasms - pathology</subject><subject>Humans</subject><subject>Intestinal Mucosa - pathology</subject><subject>Middle Aged</subject><subject>Precancerous Conditions - pathology</subject><subject>Retrospective Studies</subject><subject>Risk</subject><subject>Time Factors</subject><issn>0016-5085</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j01LxDAYhHPwa139Bwo9iR66vmmaTXKUZf2AFQX1XJI00Uja1CQV9t9b2MXLDAzD8AxClxgWGPDy9g0mLSlwes3EDQeMRUkP0Ow_PkGnKX0DgCAcH6MjRjkmMEPrZ-ndZy_7XAwhmz476YtgC_0VQ-90MXptoszu1xQ6eJddWhSv0XjXuV7GbRHNEGI-Q4dW-mTO9z5HH_fr99VjuXl5eFrdbcqhAprLVluqbbVcWtlyBZK1NVUTLKkxZUaJikNlCZ6ghRFEVRgkB6tka5VmArdkjq52u0MMP6NJuelc0sZ72ZswpobVNWG0xlPxYl8cVWfaZoium3Cb3W3yB9X9WVM</recordid><startdate>197901</startdate><enddate>197901</enddate><creator>Nugent, F W</creator><creator>Haggit, R C</creator><creator>Colcher, H</creator><creator>Kutteruf, G C</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197901</creationdate><title>Malignant potential of chronic ulcerative colitis. Preliminary report</title><author>Nugent, F W ; Haggit, R C ; Colcher, H ; Kutteruf, G C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p205t-dcf5cf266fad8b0a7d45b80134157eb92802f310019e93b210a80fbadfbc791d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biopsy</topic><topic>Child</topic><topic>Colectomy</topic><topic>Colitis, Ulcerative - complications</topic><topic>Colitis, Ulcerative - pathology</topic><topic>Colon - pathology</topic><topic>Colonic Neoplasms - etiology</topic><topic>Colonic Neoplasms - pathology</topic><topic>Humans</topic><topic>Intestinal Mucosa - pathology</topic><topic>Middle Aged</topic><topic>Precancerous Conditions - pathology</topic><topic>Retrospective Studies</topic><topic>Risk</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nugent, F W</creatorcontrib><creatorcontrib>Haggit, R C</creatorcontrib><creatorcontrib>Colcher, H</creatorcontrib><creatorcontrib>Kutteruf, G C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Gastroenterology (New York, N.Y. 1943)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nugent, F W</au><au>Haggit, R C</au><au>Colcher, H</au><au>Kutteruf, G C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Malignant potential of chronic ulcerative colitis. Preliminary report</atitle><jtitle>Gastroenterology (New York, N.Y. 1943)</jtitle><addtitle>Gastroenterology</addtitle><date>1979-01</date><risdate>1979</risdate><volume>76</volume><issue>1</issue><spage>1</spage><epage>5</epage><pages>1-5</pages><issn>0016-5085</issn><abstract>Prior studies confirm the increased incidence of carcinoma of the colon in chronic ulcerative colitis. The authors reviewed clinical and histologic data retrospectively in 23 patients with colon carcinoma and chronic ulcerative colitis. Twenty-two of these patients had dysplasia of colonic epithelium remote from the cancer. The authors prospectively reviewed clinical data and rectal and colonoscopic biopsy specimens on 36 patients with chronic ulcerative colitis, 12 with Crohn's colitis, and 12 with miscellaneous disorders. Eight patients with chronic ulcerative colitis had dysplasia; 6 have had colectomy, and 2 of these had carcinoma. No patient without chronic ulcerative colitis had dysplasia. Patients with chronic ulcerative colitis should have periodic rectal and colonoscopic biopsies, and those with moderate to marked dysplasia require colectomy because of the increased risk of colon carcinoma.</abstract><cop>United States</cop><pmid>758130</pmid><doi>10.1016/S0016-5085(79)80119-5</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0016-5085 |
| ispartof | Gastroenterology (New York, N.Y. 1943), 1979-01, Vol.76 (1), p.1-5 |
| issn | 0016-5085 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74437541 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Biopsy Child Colectomy Colitis, Ulcerative - complications Colitis, Ulcerative - pathology Colon - pathology Colonic Neoplasms - etiology Colonic Neoplasms - pathology Humans Intestinal Mucosa - pathology Middle Aged Precancerous Conditions - pathology Retrospective Studies Risk Time Factors |
| title | Malignant potential of chronic ulcerative colitis. Preliminary report |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T14%3A56%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Malignant%20potential%20of%20chronic%20ulcerative%20colitis.%20Preliminary%20report&rft.jtitle=Gastroenterology%20(New%20York,%20N.Y.%201943)&rft.au=Nugent,%20F%20W&rft.date=1979-01&rft.volume=76&rft.issue=1&rft.spage=1&rft.epage=5&rft.pages=1-5&rft.issn=0016-5085&rft_id=info:doi/10.1016/S0016-5085(79)80119-5&rft_dat=%3Cproquest_pubme%3E74437541%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=74437541&rft_id=info:pmid/758130&rfr_iscdi=true |