Arteriolar rarefaction in the conjunctiva of human essential hypertensives
Hypertension has been shown to have a component of increased vascular resistance. In general, the terms increased resistance and vasoconstriction have been used interchangeably. This study demonstrates that in the bulbar conjunctiva of human essential hypertensives, the decrease in number of arterio...
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| Veröffentlicht in: | Microvascular research 1978-11, Vol.16 (3), p.369-372 |
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| creator | Harper, Robert N. Moore, Michael A. Marr, Melissa C. Watts, L.Earl Hutchins, Phillip M. |
| description | Hypertension has been shown to have a component of increased vascular resistance. In general, the terms increased resistance and vasoconstriction have been used interchangeably. This study demonstrates that in the bulbar conjunctiva of human essential hypertensives, the decrease in number of arterioles may be just as significant as the arteriolar constriction. When compared to 12 age and sex matched normotensive controls, 12 untreated essential hypertensives had a 20% reduction in arteriolar density and a 5% decrease in arteriolar diameter. Both of these findings were significant at the 5% level. In a calculated “Poiseuille resistance,” the vessel rarefaction and the vessel constriction would contribute approximately equally to the increased resistance. These findings support the contention that microcirculatory density
and caliber should be considered in discussions of alterations of vascular resistance. |
| doi_str_mv | 10.1016/0026-2862(78)90070-5 |
| format | Article |
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| ispartof | Microvascular research, 1978-11, Vol.16 (3), p.369-372 |
| issn | 0026-2862 1095-9319 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adult Arterioles - physiopathology Conjunctiva - physiopathology Humans Hypertension - physiopathology Vascular Resistance |
| title | Arteriolar rarefaction in the conjunctiva of human essential hypertensives |
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