Silver-Catalyzed Intramolecular Cyclization of o-(1-Alkynyl)benzamides: Efficient Synthesis of (1H)-Isochromen-1-imines

An efficient avenue for the facile and atom‐economic synthesis of (1H)‐isochromen‐1‐imines has been developed, and a broad spectrum of substrates can participate in the process effectively to produce the desired products in good yields. Significantly, this is the first report of the synthesis of (1H)‐isochromen‐1‐imines that involves a silver(I)‐catalyzed, regiocontrolled intramolecular addition of the carbonyl group of the amide moiety towards an alkyne.