Regulation of lifespan by sensory perception in Caenorhabditis elegans

Caenorhabditis elegans senses environmental signals through ciliated sensory neurons located primarily in sensory organs in the head and tail. Cilia function as sensory receptors, and mutants with defective sensory cilia have impaired sensory perception 1 , 2 . Cilia are membrane-bound microtubule-b...

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Veröffentlicht in:	Nature (London) 1999-12, Vol.402 (6763), p.804-809
Hauptverfasser:	Apfeld, Javier, Kenyon, Cynthia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry. Physiology. Immunology. Molecular biology Biological and medical sciences Biology Caenorhabditis elegans Caenorhabditis elegans Proteins Cilia Forkhead Transcription Factors Fundamental and applied biological sciences. Psychology Genes, Helminth Germ Cells - physiology Helminth Proteins - genetics Helminth Proteins - physiology Humanities and Social Sciences Invertebrates Larva letter Life span Longevity - genetics Longevity - physiology multidisciplinary Mutation Nemathelminthia. Plathelmintha Neurons, Afferent - physiology Perception Physiology. Development Receptor, Insulin - genetics Receptor, Insulin - physiology Science Science (multidisciplinary) Sensory Deprivation sensory perception Transcription Factors - genetics Transcription Factors - physiology
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