Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose

Cyclic ADP-ribose (cADPR) is a natural compound that mobilizes calcium ions in several eukaryotic cells. Although it can lead to the release of calcium ions in T lymphocytes, it has not been firmly established as a second messenger in these cells. Here, using high-performance liquid chromatography a...

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Veröffentlicht in:	Nature (London) 1999-03, Vol.398 (6722), p.70-73
Hauptverfasser:	Guse, Andreas H, da Silva, Cristina P, Berg, Ingeborg, Skapenko, Alla L, Weber, Karin, Heyer, Petra, Hohenegger, Martin, Ashamu, Gloria A, Schulze-Koops, Hendrik, Potter, Barry V. L, Mayr, Georg W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate Ribose - analogs & derivatives Adenosine Diphosphate Ribose - antagonists & inhibitors Adenosine Diphosphate Ribose - metabolism Adenosine Diphosphate Ribose - pharmacology Calcium Calcium - metabolism Calcium channels Calcium Signaling CD3 Complex - immunology CD3 Complex - metabolism Cellular biology Chromatography, High Pressure Liquid Cyclic ADP-Ribose Enzyme Activation Enzymes Humans Inositol 1,4,5-Trisphosphate - antagonists & inhibitors Inositol 1,4,5-Trisphosphate - metabolism Ions Jurkat Cells Liquid chromatography Lymphocyte Activation Lymphocytes Ryanodine - metabolism Ryanodine Receptor Calcium Release Channel - metabolism Second Messenger Systems T-Lymphocytes - immunology T-Lymphocytes - metabolism
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