Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking

Essential to the dendritic cell system of antigen-presenting cells are the veiled dendritic cells that traverse afferent lymph to enter lymph nodes, where they initiate immune responses. The origin of veiled cells, which were discovered 20 years ago, is unclear. Monocytes cultured with endothelium d...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1998-10, Vol.282 (5388), p.480-483
Hauptverfasser:	Randolph, Gwendalyn J., Beaulieu, Sylvie, Lebecque, Serge, Steinman, Ralph M., Muller, William A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen presenting cells Antigens, CD - analysis Biological and medical sciences Carrier Proteins - analysis Cell Count Cell Differentiation Cell Movement Cells Cells, Cultured Cellular biology Collagen Collagens Cultured cells Dendritic cells Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - physiology Endothelial cells Endothelium Endothelium, Vascular - cytology Endothelium, Vascular - physiology Fundamental and applied biological sciences. Psychology Fundamental immunology HLA-DR Antigens - analysis Humans Immune system Immunobiology Immunology Individualized Instruction Lymph Lymphocyte Activation Lymphocyte Culture Test, Mixed Lymphocytes Macrophages Macrophages - cytology Macrophages - immunology Macrophages - physiology Microfilament Proteins - analysis Migration Patterns Monocytes Monocytes - cytology Monocytes - immunology Monocytes - physiology Monocytes, macrophages Myeloid cells: ontogeny, maturation, markers, receptors Phagocytosis Physiological aspects Stimuli T lymphocytes T-Lymphocytes - immunology
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