Bacterial Biofilms: A Common Cause of Persistent Infections
Bacteria that attach to surfaces aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. Formation of these sessile communities and their inherent resistance to antimicrobial agents are at the root of many persistent and chronic bacterial infections. Studies of biofilms hav...
Gespeichert in:
| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1999-05, Vol.284 (5418), p.1318-1322 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1322 |
|---|---|
| container_issue | 5418 |
| container_start_page | 1318 |
| container_title | Science (American Association for the Advancement of Science) |
| container_volume | 284 |
| creator | Costerton, J. W. Stewart, Philip S. Greenberg, E. P. |
| description | Bacteria that attach to surfaces aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. Formation of these sessile communities and their inherent resistance to antimicrobial agents are at the root of many persistent and chronic bacterial infections. Studies of biofilms have revealed differentiated, structured groups of cells with community properties. Recent advances in our understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections. |
| doi_str_mv | 10.1126/science.284.5418.1318 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_743638215</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A54796274</galeid><jstor_id>2899085</jstor_id><sourcerecordid>A54796274</sourcerecordid><originalsourceid>FETCH-LOGICAL-c833t-8b3d99ada316104851262b5bd99e5088b6d590c775f9fd4c8956b849b512ea003</originalsourceid><addsrcrecordid>eNqN0l2r0zAYB_AgimdOv4FKOYh6cTqTpkkTvdqGzsFwgi-3IU2fjow2OSYd6Lc3Y0OdDB25COT5JSR5_gg9IXhCSMFfRWPBGZgUopywkogJoUTcQSOCJctlgeldNMKY8lzgil2hBzFuMU41Se-jK4IpLaXAI_Rmps0Aweoum1nf2q6Pr7NpNvd9710217sImW-zjxCijQO4IVu6FsxgvYsP0b1WdxEeHecx-vLu7ef5-3y1Xizn01VuBKVDLmraSKkbTQknuBQsXb-oWZ0WgWEhat4wiU1VsVa2TWmEZLwWpawTBJ3eMEYvDufeBv9tB3FQvY0Guk478LuoqpJyKgrCknz-T8llVZVY8v9CUhVlVfA9vP4Lbv0uuPRcVRDKOBakSujmgDa6A2Vd64egzQYcBN15B-lbQU1ZWUlepMuOUX6Gp9FAb805__LEJzLA92GTmhPV8tOHi-n668V0triUisXqhN6co8Z3HWxApVzM1yecHbgJPsYArboNttfhhyJY7XOujjlXKedqn3O1z3na9_TYll3dQ_PHrkOwE3h2BDoa3bVBO2PjbycYJXLPHh_YNg4-_CoXQkqcyE_EiQiu</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>213560817</pqid></control><display><type>article</type><title>Bacterial Biofilms: A Common Cause of Persistent Infections</title><source>American Association for the Advancement of Science</source><source>Jstor Complete Legacy</source><source>MEDLINE</source><creator>Costerton, J. W. ; Stewart, Philip S. ; Greenberg, E. P.</creator><creatorcontrib>Costerton, J. W. ; Stewart, Philip S. ; Greenberg, E. P.</creatorcontrib><description>Bacteria that attach to surfaces aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. Formation of these sessile communities and their inherent resistance to antimicrobial agents are at the root of many persistent and chronic bacterial infections. Studies of biofilms have revealed differentiated, structured groups of cells with community properties. Recent advances in our understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.284.5418.1318</identifier><identifier>PMID: 10334980</identifier><identifier>CODEN: SCIEAS</identifier><language>eng</language><publisher>Washington, DC: American Society for the Advancement of Science</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Antimicrobials ; Bacteria ; Bacterial diseases ; Bacterial infections ; Bacterial Infections - microbiology ; Biofilms ; Biofilms - drug effects ; Biofilms - growth & development ; Biological and medical sciences ; Communities ; Community Relations ; Cystic Fibrosis - microbiology ; Developmental biology ; Drug Resistance, Microbial ; Equipment Contamination ; General aspects ; Genes, Bacterial ; Genetics ; Humans ; Infections ; Infectious diseases ; Lactones ; Lung - microbiology ; Lungs ; Mathematical Models ; Medical sciences ; Microbial mats ; Microbiology ; Phagocytes ; Population Distribution ; Pseudomonas aeruginosa - genetics ; Pseudomonas aeruginosa - physiology ; Pseudomonas Infections - drug therapy ; Pseudomonas Infections - microbiology ; Reviews ; Space life sciences</subject><ispartof>Science (American Association for the Advancement of Science), 1999-05, Vol.284 (5418), p.1318-1322</ispartof><rights>Copyright 1999 American Association for the Advancement of Science</rights><rights>1999 INIST-CNRS</rights><rights>COPYRIGHT 1999 American Association for the Advancement of Science</rights><rights>COPYRIGHT 1999 American Association for the Advancement of Science</rights><rights>Copyright American Association for the Advancement of Science May 21, 1999</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c833t-8b3d99ada316104851262b5bd99e5088b6d590c775f9fd4c8956b849b512ea003</citedby><cites>FETCH-LOGICAL-c833t-8b3d99ada316104851262b5bd99e5088b6d590c775f9fd4c8956b849b512ea003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/2899085$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/2899085$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,2871,2872,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1853190$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10334980$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Costerton, J. W.</creatorcontrib><creatorcontrib>Stewart, Philip S.</creatorcontrib><creatorcontrib>Greenberg, E. P.</creatorcontrib><title>Bacterial Biofilms: A Common Cause of Persistent Infections</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Bacteria that attach to surfaces aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. Formation of these sessile communities and their inherent resistance to antimicrobial agents are at the root of many persistent and chronic bacterial infections. Studies of biofilms have revealed differentiated, structured groups of cells with community properties. Recent advances in our understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Antimicrobials</subject><subject>Bacteria</subject><subject>Bacterial diseases</subject><subject>Bacterial infections</subject><subject>Bacterial Infections - microbiology</subject><subject>Biofilms</subject><subject>Biofilms - drug effects</subject><subject>Biofilms - growth & development</subject><subject>Biological and medical sciences</subject><subject>Communities</subject><subject>Community Relations</subject><subject>Cystic Fibrosis - microbiology</subject><subject>Developmental biology</subject><subject>Drug Resistance, Microbial</subject><subject>Equipment Contamination</subject><subject>General aspects</subject><subject>Genes, Bacterial</subject><subject>Genetics</subject><subject>Humans</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Lactones</subject><subject>Lung - microbiology</subject><subject>Lungs</subject><subject>Mathematical Models</subject><subject>Medical sciences</subject><subject>Microbial mats</subject><subject>Microbiology</subject><subject>Phagocytes</subject><subject>Population Distribution</subject><subject>Pseudomonas aeruginosa - genetics</subject><subject>Pseudomonas aeruginosa - physiology</subject><subject>Pseudomonas Infections - drug therapy</subject><subject>Pseudomonas Infections - microbiology</subject><subject>Reviews</subject><subject>Space life sciences</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0l2r0zAYB_AgimdOv4FKOYh6cTqTpkkTvdqGzsFwgi-3IU2fjow2OSYd6Lc3Y0OdDB25COT5JSR5_gg9IXhCSMFfRWPBGZgUopywkogJoUTcQSOCJctlgeldNMKY8lzgil2hBzFuMU41Se-jK4IpLaXAI_Rmps0Aweoum1nf2q6Pr7NpNvd9710217sImW-zjxCijQO4IVu6FsxgvYsP0b1WdxEeHecx-vLu7ef5-3y1Xizn01VuBKVDLmraSKkbTQknuBQsXb-oWZ0WgWEhat4wiU1VsVa2TWmEZLwWpawTBJ3eMEYvDufeBv9tB3FQvY0Guk478LuoqpJyKgrCknz-T8llVZVY8v9CUhVlVfA9vP4Lbv0uuPRcVRDKOBakSujmgDa6A2Vd64egzQYcBN15B-lbQU1ZWUlepMuOUX6Gp9FAb805__LEJzLA92GTmhPV8tOHi-n668V0triUisXqhN6co8Z3HWxApVzM1yecHbgJPsYArboNttfhhyJY7XOujjlXKedqn3O1z3na9_TYll3dQ_PHrkOwE3h2BDoa3bVBO2PjbycYJXLPHh_YNg4-_CoXQkqcyE_EiQiu</recordid><startdate>19990521</startdate><enddate>19990521</enddate><creator>Costerton, J. W.</creator><creator>Stewart, Philip S.</creator><creator>Greenberg, E. P.</creator><general>American Society for the Advancement of Science</general><general>American Association for the Advancement of Science</general><general>The American Association for the Advancement of Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8GL</scope><scope>IBG</scope><scope>IOV</scope><scope>ISN</scope><scope>0-V</scope><scope>3V.</scope><scope>7QF</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QQ</scope><scope>7QR</scope><scope>7SC</scope><scope>7SE</scope><scope>7SN</scope><scope>7SP</scope><scope>7SR</scope><scope>7SS</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7TK</scope><scope>7TM</scope><scope>7U5</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88B</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>D1I</scope><scope>DWQXO</scope><scope>F28</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9-</scope><scope>K9.</scope><scope>KB.</scope><scope>KR7</scope><scope>L6V</scope><scope>L7M</scope><scope>LK8</scope><scope>L~C</scope><scope>L~D</scope><scope>M0K</scope><scope>M0P</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>MBDVC</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PCBAR</scope><scope>PDBOC</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>R05</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>19990521</creationdate><title>Bacterial Biofilms: A Common Cause of Persistent Infections</title><author>Costerton, J. W. ; Stewart, Philip S. ; Greenberg, E. P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c833t-8b3d99ada316104851262b5bd99e5088b6d590c775f9fd4c8956b849b512ea003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibiotics</topic><topic>Antimicrobials</topic><topic>Bacteria</topic><topic>Bacterial diseases</topic><topic>Bacterial infections</topic><topic>Bacterial Infections - microbiology</topic><topic>Biofilms</topic><topic>Biofilms - drug effects</topic><topic>Biofilms - growth & development</topic><topic>Biological and medical sciences</topic><topic>Communities</topic><topic>Community Relations</topic><topic>Cystic Fibrosis - microbiology</topic><topic>Developmental biology</topic><topic>Drug Resistance, Microbial</topic><topic>Equipment Contamination</topic><topic>General aspects</topic><topic>Genes, Bacterial</topic><topic>Genetics</topic><topic>Humans</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Lactones</topic><topic>Lung - microbiology</topic><topic>Lungs</topic><topic>Mathematical Models</topic><topic>Medical sciences</topic><topic>Microbial mats</topic><topic>Microbiology</topic><topic>Phagocytes</topic><topic>Population Distribution</topic><topic>Pseudomonas aeruginosa - genetics</topic><topic>Pseudomonas aeruginosa - physiology</topic><topic>Pseudomonas Infections - drug therapy</topic><topic>Pseudomonas Infections - microbiology</topic><topic>Reviews</topic><topic>Space life sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Costerton, J. W.</creatorcontrib><creatorcontrib>Stewart, Philip S.</creatorcontrib><creatorcontrib>Greenberg, E. P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: High School</collection><collection>Gale In Context: Biography</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Canada</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Aluminium Industry Abstracts</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Ecology Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Education Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Earth, Atmospheric & Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Education Collection</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Civil Engineering Abstracts</collection><collection>ProQuest Engineering Collection</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ProQuest Biological Science Collection</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Agricultural Science Database</collection><collection>Education Database (ProQuest)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Research Library (Corporate)</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Earth, Atmospheric & Aquatic Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest One Education</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>University of Michigan</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Costerton, J. W.</au><au>Stewart, Philip S.</au><au>Greenberg, E. P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bacterial Biofilms: A Common Cause of Persistent Infections</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1999-05-21</date><risdate>1999</risdate><volume>284</volume><issue>5418</issue><spage>1318</spage><epage>1322</epage><pages>1318-1322</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><coden>SCIEAS</coden><abstract>Bacteria that attach to surfaces aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. Formation of these sessile communities and their inherent resistance to antimicrobial agents are at the root of many persistent and chronic bacterial infections. Studies of biofilms have revealed differentiated, structured groups of cells with community properties. Recent advances in our understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.</abstract><cop>Washington, DC</cop><pub>American Society for the Advancement of Science</pub><pmid>10334980</pmid><doi>10.1126/science.284.5418.1318</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 1999-05, Vol.284 (5418), p.1318-1322 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_743638215 |
| source | American Association for the Advancement of Science; Jstor Complete Legacy; MEDLINE |
| subjects | Anti-Bacterial Agents - therapeutic use Antibiotics Antimicrobials Bacteria Bacterial diseases Bacterial infections Bacterial Infections - microbiology Biofilms Biofilms - drug effects Biofilms - growth & development Biological and medical sciences Communities Community Relations Cystic Fibrosis - microbiology Developmental biology Drug Resistance, Microbial Equipment Contamination General aspects Genes, Bacterial Genetics Humans Infections Infectious diseases Lactones Lung - microbiology Lungs Mathematical Models Medical sciences Microbial mats Microbiology Phagocytes Population Distribution Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - physiology Pseudomonas Infections - drug therapy Pseudomonas Infections - microbiology Reviews Space life sciences |
| title | Bacterial Biofilms: A Common Cause of Persistent Infections |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T17%3A23%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Bacterial%20Biofilms:%20A%20Common%20Cause%20of%20Persistent%20Infections&rft.jtitle=Science%20(American%20Association%20for%20the%20Advancement%20of%20Science)&rft.au=Costerton,%20J.%20W.&rft.date=1999-05-21&rft.volume=284&rft.issue=5418&rft.spage=1318&rft.epage=1322&rft.pages=1318-1322&rft.issn=0036-8075&rft.eissn=1095-9203&rft.coden=SCIEAS&rft_id=info:doi/10.1126/science.284.5418.1318&rft_dat=%3Cgale_proqu%3EA54796274%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=213560817&rft_id=info:pmid/10334980&rft_galeid=A54796274&rft_jstor_id=2899085&rfr_iscdi=true |