A model retinal interface based on directed neuronal growth for single cell stimulation

In this work, we use cell micropatterning technologies to direct neuronal growth to individual electrodes, and demonstrate that such an approach can achieve selective stimulation and lower stimulation thresholds than current field-effect based retinal prostheses. Rat retinal ganglion cells (RGCs) we...

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Veröffentlicht in:	Biomedical microdevices 2006-06, Vol.8 (2), p.141-150
Hauptverfasser:	Mehenti, Neville Z, Tsien, Greg S, Leng, Theodore, Fishman, Harvey A, Bent, Stacey F
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals Cell Culture Techniques - instrumentation Cell Culture Techniques - methods Cell Polarity - physiology Cell Proliferation Cells, Cultured Electric Stimulation - instrumentation Electric Stimulation - methods Equipment Design Equipment Failure Analysis Microelectrodes Nerve Net - cytology Nerve Net - physiology Rats Rats, Sprague-Dawley Retinal Ganglion Cells - cytology Retinal Ganglion Cells - physiology
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