X-inactivation profile reveals extensive variability in X-linked gene expression in females

The human X chromosome The detailed sequence of the human X chromosome is published this week, together with a survey of inactivated X genes in females. Females have two Xs and males have one X and a Y; to make the gene dosage equivalent, females inactivate almost an entire chromosome. The X inactiv...

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Veröffentlicht in:Nature (London) 2005-03, Vol.434 (7031), p.400-404
Hauptverfasser: Carrel, Laura, Willard, Huntington F.
Format: Artikel
Sprache:eng
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