The Bcl-2 Protein Family: Arbiters of Cell Survival

Bcl-2 and related cytoplasmic proteins are key regulators of apoptosis, the cell suicide program critical for development, tissue homeostasis, and protection against pathogens. Those most similar to Bcl-2 promote cell survival by inhibiting adapters needed for activation of the proteases (caspases)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1998-08, Vol.281 (5381), p.1322-1326
Hauptverfasser:	Adams, Jerry M., Cory, Suzanne
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & physiology Animals Apoptosis Cell Cycle Cell death Cell lines Cell research Cell Survival Cells Cysteine Endopeptidases - metabolism Cytokines Cytokines - physiology Cytological research Family (Sociological Unit) Family members Genes, bcl-2 Humans Neoplasms - etiology Neoplasms - pathology Neoplasms - therapy Neurons Oncogenes Organelles Organelles - physiology Proteins Proto-Oncogene Proteins c-bcl-2 - chemistry Proto-Oncogene Proteins c-bcl-2 - physiology Reviews Suicide T lymphocytes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!