Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

THYROID hormones and retinoic acid function through nuclear receptors that belong to the steroid/thyroid-hormone receptor superfamily (reviewed in refs 1–4). Thyroid hormone receptors (TRs) and retinoic acid receptors (RARs) require auxiliary nuclear proteins for efficient DNA binding 5–10 . Here we...

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Veröffentlicht in:	Nature (London) 1992-01, Vol.355 (6359), p.441-446
Hauptverfasser:	Zhang, Xiao-kun, Hoffmann, Birgit, Tran, Paul B.-V, Graupner, Gerhart, Pfahl, Magnus
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Carrier Proteins - genetics Carrier Proteins - metabolism Cell Line Cell receptors Cell structures and functions Cellular biology Chromosome Deletion Cloning, Molecular DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Female Fundamental and applied biological sciences. Psychology Gene Library Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Hormones Humanities and Social Sciences Humans Kinetics letter Macromolecular Substances Molecular and cellular biology Molecular Sequence Data multidisciplinary Nuclear Proteins - metabolism Oligodeoxyribonucleotides Placenta - physiology Polymerase Chain Reaction - methods Pregnancy Protein Biosynthesis Proteins Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Receptors, Retinoic Acid Receptors, Thyroid Hormone - genetics Receptors, Thyroid Hormone - metabolism Restriction Mapping Retinoid X Receptors Science Science (multidisciplinary) Thyroid Transcription Factors Transcription, Genetic - drug effects Transfection Tretinoin - metabolism Tretinoin - pharmacology Triiodothyronine - pharmacology
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