A preliminary investigation demonstrating the effect of quercetin on the expression of genes related to cell-cycle arrest, apoptosis and xenobiotic metabolism in human CO115 colon-adenocarcinoma cells using DNA microarray

The role of the natural dietary flavonoid chemical quercetin (an antioxidant) in the prevention and treatment of colon cancer is receiving a great deal of attention. However, little is known about the molecular mechanisms of action of this flavonoid. In the present study, whole genome DNA microarray...

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Veröffentlicht in:	Biotechnology and applied biochemistry 2006-07, Vol.45 (1), p.29-36
Hauptverfasser:	Murtaza, Imtiyaz, Marra, Giancarlo, Schlapbach, Ralph, Patrignani, Andrea, Künzli, Marzana, Wagner, Ulrich, Sabates, Jacob, Dutt, Amit
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - drug effects Biological and medical sciences Biotechnology cell cycle Cell Cycle - drug effects Cell Line, Tumor chemoprevention Colonic Neoplasms - metabolism Colonic Neoplasms - prevention & control differential expression DNA microarray Flavonoids - pharmacology Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation - drug effects Humans Oligonucleotide Array Sequence Analysis - methods quercetin Quercetin - pharmacology Up-Regulation - drug effects Xenobiotics - metabolism
Online-Zugang:	Volltext
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