New components of the spliced leader RNP required for nematode trans-splicing

Pre-messenger-RNA maturation in nematodes and in several other lower eukaryotic phyla involves spliced leader (SL) addition trans -splicing 1 , 2 . In this unusual RNA processing reaction, a short common 5′ exon, the SL, is affixed to the 5′-most exon of multiple pre-mRNAs. The nematode SL is derive...

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Veröffentlicht in:	Nature (London) 2002-06, Vol.417 (6889), p.667-670
Hauptverfasser:	Denker, John A., Zuckerman, David M., Maroney, Patricia A., Nilsen, Timothy W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ascaris - genetics Biological and medical sciences Exons - genetics Fundamental and applied biological sciences. Psychology Humanities and Social Sciences Introns - genetics letter Molecular and cellular biology Molecular biology Molecular genetics Molecular Weight multidisciplinary Nematodes Protein Binding Protein Subunits Proteins Ribonucleic acid Ribonucleoproteins - chemistry Ribonucleoproteins - genetics Ribonucleoproteins - metabolism RNA RNA Precursors - genetics RNA Precursors - metabolism RNA Splicing - genetics RNA, Spliced Leader - genetics RNA, Spliced Leader - metabolism Science Science (multidisciplinary) Spliceosomes - chemistry Spliceosomes - metabolism Trans-Splicing - genetics Transcription. Transcription factor. Splicing. Rna processing Worms
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