New cell lines from mouse epiblast share defining features with human embryonic stem cells

A new type of stem cell Human embryonic stem (ES) cells are potentially important in therapy because they are pluripotent, capable of differentiating into virtually any cell type given appropriate encouragement. One obstacle to progress in research on them has been the baffling differences between h...

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Veröffentlicht in:	Nature 2007-07, Vol.448 (7150), p.196-199
Hauptverfasser:	Tesar, Paul J., Chenoweth, Josh G., Brook, Frances A., Davies, Timothy J., Evans, Edward P., Mack, David L., Gardner, Richard L., McKay, Ronald D. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models in research Animals Biological and medical sciences Biology Cell Culture Techniques Cell Differentiation Cell differentiation, maturation, development, hematopoiesis Cell Line Cell lines Cell physiology Embryo Implantation Embryonic stem cells Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Embryos Fundamental and applied biological sciences. Psychology Gene Expression Human Humanities and Social Sciences Humans Implantation Integrity letter Mice Molecular and cellular biology multidisciplinary Origins Pluripotent Stem Cells - cytology Pluripotent Stem Cells - metabolism Rodents Science Science (multidisciplinary) Signal Transduction Stem cells Transcription Factors - metabolism
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