Antibody-Based Bio-Nanotube Membranes for Enantiomeric Drug Separations

Synthetic bio-nanotube membranes were developed and used to separate two enantiomers of a chiral drug. These membranes are based on alumina films that have cylindrical pores with monodisperse nanoscopic diameters (for example, 20 nanometers). Silica nanotubes were chemically synthesized within the p...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2002-06, Vol.296 (5576), p.2198-2200
Hauptverfasser:	Lee, Sang Bok, Mitchell, David T., Trofin, Lacramioara, Nevanen, Tarja K., Söderlund, Hans, Martin, Charles R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aluminum Oxide Analysis Antibodies Biological and medical sciences Chemistry Circles Diffusion Dimethyl Sulfoxide Drugs Enantiomers General pharmacology Magnetic fields Medical sciences Membranes Membranes, Artificial Molecules Nanotechnology Nanotubes Narcotics Nitriles - chemistry Nitriles - immunology Nitriles - isolation & purification P branes Permeability Pharmacology. Drug treatments Separation (Technology) Silicon Dioxide Sol gel processes Stereoisomerism String theory Technology, Pharmaceutical Triazoles - chemistry Triazoles - immunology Triazoles - isolation & purification
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