Enhanced and Delayed Stress-Induced Alcohol Drinking in Mice Lacking Functional CRH1 Receptors

There is a relation between stress and alcohol drinking. We show that the corticotropin-releasing hormone (CRH) system that mediates endocrine and behavioral responses to stress plays a role in the control of long-term alcohol drinking. In mice lacking a functional CRH1 receptor, stress leads to enh...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 2002-05, Vol.296 (5569), p.931-933
Hauptverfasser: Sillaber, Inge, Rammes, Gerhard, Zimmermann, Stephan, Mahal, Beatrice, Zieglgänsberger, Walter, Wurst, Wolfgang, Holsboer, Florian, Spanagel, Rainer
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Sprache:eng
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