Movement Intention After Parietal Cortex Stimulation in Humans
Parietal and premotor cortex regions are serious contenders for bringing motor intentions and motor responses into awareness. We used electrical stimulation in seven patients undergoing awake brain surgery. Stimulating the right inferior parietal regions triggered a strong intention and desire to mo...
Gespeichert in:
| Veröffentlicht in: | Science (American Association for the Advancement of Science) 2009-05, Vol.324 (5928), p.811-813 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 813 |
|---|---|
| container_issue | 5928 |
| container_start_page | 811 |
| container_title | Science (American Association for the Advancement of Science) |
| container_volume | 324 |
| creator | Desmurget, Michel Reilly, Karen T Richard, Nathalie Szathmari, Alexandru Mottolese, Carmine Sirigu, Angela |
| description | Parietal and premotor cortex regions are serious contenders for bringing motor intentions and motor responses into awareness. We used electrical stimulation in seven patients undergoing awake brain surgery. Stimulating the right inferior parietal regions triggered a strong intention and desire to move the contralateral hand, arm, or foot, whereas stimulating the left inferior parietal region provoked the intention to move the lips and to talk. When stimulation intensity was increased in parietal areas, participants believed they had really performed these movements, although no electromyographic activity was detected. Stimulation of the premotor region triggered overt mouth and contralateral limb movements. Yet, patients firmly denied that they had moved. Conscious intention and motor awareness thus arise from increased parietal activity before movement execution. |
| doi_str_mv | 10.1126/science.1169896 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_743321703</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>20493908</jstor_id><sourcerecordid>20493908</sourcerecordid><originalsourceid>FETCH-LOGICAL-c557t-6c9ad5a88904f30b0bd3d5f3089ddcb18465a7d6cfcf09aa7094651d13cd5d83</originalsourceid><addsrcrecordid>eNqF0c1rFDEUAPAgFruunj2pg2A9jX35mHxchLJYW6gotJ5DNsnILDNJm2Sk_vdm3cGCBz29JO-XR14eQi8wvMeY8NNsBx-srxuupOKP0AqD6lpFgD5GKwDKWwmiO0ZPc94B1JyiT9AxVoxQSWGFPnyOP_zkQ2kuQ6lhiKE564tPzVeTBl_M2GxiKv6-uS7DNI_mtxhCczFPJuRn6Kg3Y_bPl7hGN-cfbzYX7dWXT5ebs6vWdp0oLbfKuM5IqYD1FLawddR1dSWVc3aLJeOdEY7b3vagjBGg6gl2mFrXOUnX6N2h7G2Kd7PPRU9Dtn4cTfBxzlowSgkWQKs8-afkgmDMqPwvJMABM7aHb_6CuzinULvVBNP6n0Tt0ekB2RRzTr7Xt2mYTPqpMej9pPQyKb1Mqt54tZSdt5N3D34ZTQVvF2CyNWOfTLBD_uMIZlKo2soavTy4XS4xPeSBKapg_7TXh3xvojbfU63x7ZoApoA5kVhQ-guj6a5C</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>213593298</pqid></control><display><type>article</type><title>Movement Intention After Parietal Cortex Stimulation in Humans</title><source>MEDLINE</source><source>Science Magazine</source><source>JSTOR Archive Collection A-Z Listing</source><creator>Desmurget, Michel ; Reilly, Karen T ; Richard, Nathalie ; Szathmari, Alexandru ; Mottolese, Carmine ; Sirigu, Angela</creator><creatorcontrib>Desmurget, Michel ; Reilly, Karen T ; Richard, Nathalie ; Szathmari, Alexandru ; Mottolese, Carmine ; Sirigu, Angela</creatorcontrib><description>Parietal and premotor cortex regions are serious contenders for bringing motor intentions and motor responses into awareness. We used electrical stimulation in seven patients undergoing awake brain surgery. Stimulating the right inferior parietal regions triggered a strong intention and desire to move the contralateral hand, arm, or foot, whereas stimulating the left inferior parietal region provoked the intention to move the lips and to talk. When stimulation intensity was increased in parietal areas, participants believed they had really performed these movements, although no electromyographic activity was detected. Stimulation of the premotor region triggered overt mouth and contralateral limb movements. Yet, patients firmly denied that they had moved. Conscious intention and motor awareness thus arise from increased parietal activity before movement execution.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.1169896</identifier><identifier>PMID: 19423830</identifier><identifier>CODEN: SCIEAS</identifier><language>eng</language><publisher>Washington, DC: American Association for the Advancement of Science</publisher><subject>Anatomy ; Behavioral neuroscience ; Biological and medical sciences ; Brain Mapping ; Cognition & reasoning ; Desire ; Electric Stimulation ; Electrical stimulation ; Electricity ; Electromyography ; Extremities - physiology ; Frontal Lobe - physiology ; Fundamental and applied biological sciences. Psychology ; Humans ; Intention ; Itching ; Medical research ; Mental stimulation ; Motor ability ; Motor cortex ; Motor Cortex - physiology ; Mouth - physiology ; Movement ; Neurology ; Parietal Lobe - physiology ; Physiological stimulation ; Tumors ; Vertebrates: nervous system and sense organs ; Volition</subject><ispartof>Science (American Association for the Advancement of Science), 2009-05, Vol.324 (5928), p.811-813</ispartof><rights>Copyright 2009 American Association for the Advancement of Science</rights><rights>2009 INIST-CNRS</rights><rights>Copyright © 2009, American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c557t-6c9ad5a88904f30b0bd3d5f3089ddcb18465a7d6cfcf09aa7094651d13cd5d83</citedby><cites>FETCH-LOGICAL-c557t-6c9ad5a88904f30b0bd3d5f3089ddcb18465a7d6cfcf09aa7094651d13cd5d83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/20493908$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/20493908$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>315,781,785,804,2885,2886,27929,27930,58022,58255</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21487914$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19423830$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Desmurget, Michel</creatorcontrib><creatorcontrib>Reilly, Karen T</creatorcontrib><creatorcontrib>Richard, Nathalie</creatorcontrib><creatorcontrib>Szathmari, Alexandru</creatorcontrib><creatorcontrib>Mottolese, Carmine</creatorcontrib><creatorcontrib>Sirigu, Angela</creatorcontrib><title>Movement Intention After Parietal Cortex Stimulation in Humans</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Parietal and premotor cortex regions are serious contenders for bringing motor intentions and motor responses into awareness. We used electrical stimulation in seven patients undergoing awake brain surgery. Stimulating the right inferior parietal regions triggered a strong intention and desire to move the contralateral hand, arm, or foot, whereas stimulating the left inferior parietal region provoked the intention to move the lips and to talk. When stimulation intensity was increased in parietal areas, participants believed they had really performed these movements, although no electromyographic activity was detected. Stimulation of the premotor region triggered overt mouth and contralateral limb movements. Yet, patients firmly denied that they had moved. Conscious intention and motor awareness thus arise from increased parietal activity before movement execution.</description><subject>Anatomy</subject><subject>Behavioral neuroscience</subject><subject>Biological and medical sciences</subject><subject>Brain Mapping</subject><subject>Cognition & reasoning</subject><subject>Desire</subject><subject>Electric Stimulation</subject><subject>Electrical stimulation</subject><subject>Electricity</subject><subject>Electromyography</subject><subject>Extremities - physiology</subject><subject>Frontal Lobe - physiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Intention</subject><subject>Itching</subject><subject>Medical research</subject><subject>Mental stimulation</subject><subject>Motor ability</subject><subject>Motor cortex</subject><subject>Motor Cortex - physiology</subject><subject>Mouth - physiology</subject><subject>Movement</subject><subject>Neurology</subject><subject>Parietal Lobe - physiology</subject><subject>Physiological stimulation</subject><subject>Tumors</subject><subject>Vertebrates: nervous system and sense organs</subject><subject>Volition</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0c1rFDEUAPAgFruunj2pg2A9jX35mHxchLJYW6gotJ5DNsnILDNJm2Sk_vdm3cGCBz29JO-XR14eQi8wvMeY8NNsBx-srxuupOKP0AqD6lpFgD5GKwDKWwmiO0ZPc94B1JyiT9AxVoxQSWGFPnyOP_zkQ2kuQ6lhiKE564tPzVeTBl_M2GxiKv6-uS7DNI_mtxhCczFPJuRn6Kg3Y_bPl7hGN-cfbzYX7dWXT5ebs6vWdp0oLbfKuM5IqYD1FLawddR1dSWVc3aLJeOdEY7b3vagjBGg6gl2mFrXOUnX6N2h7G2Kd7PPRU9Dtn4cTfBxzlowSgkWQKs8-afkgmDMqPwvJMABM7aHb_6CuzinULvVBNP6n0Tt0ekB2RRzTr7Xt2mYTPqpMej9pPQyKb1Mqt54tZSdt5N3D34ZTQVvF2CyNWOfTLBD_uMIZlKo2soavTy4XS4xPeSBKapg_7TXh3xvojbfU63x7ZoApoA5kVhQ-guj6a5C</recordid><startdate>20090508</startdate><enddate>20090508</enddate><creator>Desmurget, Michel</creator><creator>Reilly, Karen T</creator><creator>Richard, Nathalie</creator><creator>Szathmari, Alexandru</creator><creator>Mottolese, Carmine</creator><creator>Sirigu, Angela</creator><general>American Association for the Advancement of Science</general><general>The American Association for the Advancement of Science</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QQ</scope><scope>7QR</scope><scope>7SC</scope><scope>7SE</scope><scope>7SN</scope><scope>7SP</scope><scope>7SR</scope><scope>7SS</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7TK</scope><scope>7TM</scope><scope>7U5</scope><scope>7U9</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20090508</creationdate><title>Movement Intention After Parietal Cortex Stimulation in Humans</title><author>Desmurget, Michel ; Reilly, Karen T ; Richard, Nathalie ; Szathmari, Alexandru ; Mottolese, Carmine ; Sirigu, Angela</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c557t-6c9ad5a88904f30b0bd3d5f3089ddcb18465a7d6cfcf09aa7094651d13cd5d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Anatomy</topic><topic>Behavioral neuroscience</topic><topic>Biological and medical sciences</topic><topic>Brain Mapping</topic><topic>Cognition & reasoning</topic><topic>Desire</topic><topic>Electric Stimulation</topic><topic>Electrical stimulation</topic><topic>Electricity</topic><topic>Electromyography</topic><topic>Extremities - physiology</topic><topic>Frontal Lobe - physiology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Intention</topic><topic>Itching</topic><topic>Medical research</topic><topic>Mental stimulation</topic><topic>Motor ability</topic><topic>Motor cortex</topic><topic>Motor Cortex - physiology</topic><topic>Mouth - physiology</topic><topic>Movement</topic><topic>Neurology</topic><topic>Parietal Lobe - physiology</topic><topic>Physiological stimulation</topic><topic>Tumors</topic><topic>Vertebrates: nervous system and sense organs</topic><topic>Volition</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Desmurget, Michel</creatorcontrib><creatorcontrib>Reilly, Karen T</creatorcontrib><creatorcontrib>Richard, Nathalie</creatorcontrib><creatorcontrib>Szathmari, Alexandru</creatorcontrib><creatorcontrib>Mottolese, Carmine</creatorcontrib><creatorcontrib>Sirigu, Angela</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Ecology Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Desmurget, Michel</au><au>Reilly, Karen T</au><au>Richard, Nathalie</au><au>Szathmari, Alexandru</au><au>Mottolese, Carmine</au><au>Sirigu, Angela</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Movement Intention After Parietal Cortex Stimulation in Humans</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>2009-05-08</date><risdate>2009</risdate><volume>324</volume><issue>5928</issue><spage>811</spage><epage>813</epage><pages>811-813</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><coden>SCIEAS</coden><abstract>Parietal and premotor cortex regions are serious contenders for bringing motor intentions and motor responses into awareness. We used electrical stimulation in seven patients undergoing awake brain surgery. Stimulating the right inferior parietal regions triggered a strong intention and desire to move the contralateral hand, arm, or foot, whereas stimulating the left inferior parietal region provoked the intention to move the lips and to talk. When stimulation intensity was increased in parietal areas, participants believed they had really performed these movements, although no electromyographic activity was detected. Stimulation of the premotor region triggered overt mouth and contralateral limb movements. Yet, patients firmly denied that they had moved. Conscious intention and motor awareness thus arise from increased parietal activity before movement execution.</abstract><cop>Washington, DC</cop><pub>American Association for the Advancement of Science</pub><pmid>19423830</pmid><doi>10.1126/science.1169896</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 2009-05, Vol.324 (5928), p.811-813 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_743321703 |
| source | MEDLINE; Science Magazine; JSTOR Archive Collection A-Z Listing |
| subjects | Anatomy Behavioral neuroscience Biological and medical sciences Brain Mapping Cognition & reasoning Desire Electric Stimulation Electrical stimulation Electricity Electromyography Extremities - physiology Frontal Lobe - physiology Fundamental and applied biological sciences. Psychology Humans Intention Itching Medical research Mental stimulation Motor ability Motor cortex Motor Cortex - physiology Mouth - physiology Movement Neurology Parietal Lobe - physiology Physiological stimulation Tumors Vertebrates: nervous system and sense organs Volition |
| title | Movement Intention After Parietal Cortex Stimulation in Humans |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T00%3A50%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Movement%20Intention%20After%20Parietal%20Cortex%20Stimulation%20in%20Humans&rft.jtitle=Science%20(American%20Association%20for%20the%20Advancement%20of%20Science)&rft.au=Desmurget,%20Michel&rft.date=2009-05-08&rft.volume=324&rft.issue=5928&rft.spage=811&rft.epage=813&rft.pages=811-813&rft.issn=0036-8075&rft.eissn=1095-9203&rft.coden=SCIEAS&rft_id=info:doi/10.1126/science.1169896&rft_dat=%3Cjstor_proqu%3E20493908%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=213593298&rft_id=info:pmid/19423830&rft_jstor_id=20493908&rfr_iscdi=true |