Ion conduction pore is conserved among potassium channels

Potassium channels, a group of specialized membrane proteins, enable K + ions to flow selectively across cell membranes. Transmembrane K + currents underlie electrical signalling in neurons and other excitable cells. The atomic structure of a bacterial K + channel pore has been solved by means of X-...

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Veröffentlicht in:	Nature (London) 2001-10, Vol.413 (6858), p.809-813
Hauptverfasser:	Lu, Zhe, Klem, Angela M., Ramu, Yajamana
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino Acid Substitution Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - physiology Cloning, Molecular Conserved Sequence Crystallography Crystallography, X-Ray Eukaryotic Cells Humanities and Social Sciences Ion Channel Gating Ion Transport Ions Membranes Molecular Sequence Data multidisciplinary Potassium Potassium - metabolism Potassium Channels - chemistry Potassium Channels - genetics Potassium Channels - physiology Potassium Channels, Inwardly Rectifying - chemistry Potassium Channels, Inwardly Rectifying - genetics Potassium Channels, Inwardly Rectifying - physiology Prokaryotic Cells Protein Conformation Proteins Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Science Science (multidisciplinary) Sequence Homology, Amino Acid Shaker Superfamily of Potassium Channels Species Specificity Structure-Activity Relationship
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