Amino aciduria in weightlessness
Urinary excretion of amino acids by the 9 Skylab crewmen was studied as an indicator of the metabolic effects caused by exposure to the space flight environment. Intake was consistent in quality and quantity throughout the 28, 59 and 84-day flights for each of the crewmen and complete collections we...
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Veröffentlicht in: | Acta astronautica 1979-10, Vol.6 (10), p.1323-1333 |
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description | Urinary excretion of amino acids by the 9 Skylab crewmen was studied as an indicator of the metabolic effects caused by exposure to the space flight environment. Intake was consistent in quality and quantity throughout the 28, 59 and 84-day flights for each of the crewmen and complete collections were accomplished. The results indicated an increased excretion in most amino acids during the first month of flight which remained elevated in the second and third months but to a lesser extent. Additional indications of change in muscle and skeletal metabolism were observed. These results point to the desirability of obtaining additional indices of alterations in protein synthetic processes in conjunction with future space flights. |
doi_str_mv | 10.1016/0094-5765(79)90124-3 |
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Intake was consistent in quality and quantity throughout the 28, 59 and 84-day flights for each of the crewmen and complete collections were accomplished. The results indicated an increased excretion in most amino acids during the first month of flight which remained elevated in the second and third months but to a lesser extent. Additional indications of change in muscle and skeletal metabolism were observed. 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These results point to the desirability of obtaining additional indices of alterations in protein synthetic processes in conjunction with future space flights.</description><subject>Adaptation, Physiological</subject><subject>Amino Acids - metabolism</subject><subject>Amino Acids - urine</subject><subject>Energy Metabolism - physiology</subject><subject>Humans</subject><subject>Hydroxylysine - analogs & derivatives</subject><subject>Hydroxylysine - metabolism</subject><subject>Hydroxylysine - urine</subject><subject>Hydroxyproline - metabolism</subject><subject>Hydroxyproline - urine</subject><subject>Male</subject><subject>Methylhistidines - metabolism</subject><subject>Methylhistidines - urine</subject><subject>Space Flight</subject><subject>Space life sciences</subject><subject>Weightlessness</subject><issn>0094-5765</issn><issn>1879-2030</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMotlb_gcisRBejeU6SjVCKLyi40XWYJDcamUedzCj-e6e26E4Xl7P5zrnwIXRM8AXBpLjEWPNcyEKcSX2uMaE8ZztoSpTUOcUM76LpDzJBBym9YowlVXofTQjRmBIppiib17Fps9JFP3SxzGKTfUB8fukrSKkZ7xDthbJKcLTNGXq6uX5c3OXLh9v7xXyZO6Z0nxMvZaDBshCcKgtrlbCEUwGUesItJ5r6YJXnGApFsQwFZwEskTRIKljBZuh0s7vq2rcBUm_qmBxUVdlAOyQjOWNEKPEvSBlXQik6gnwDuq5NqYNgVl2sy-7TEGzWCs3aj1n7MVKbb4WGjbWT7f5ga_C_pa2zEbjaADDqeI_QmeQiNA587MD1xrfx7w9fs3J-Iw</recordid><startdate>197910</startdate><enddate>197910</enddate><creator>Leach, C.S.</creator><creator>Rambaut, P.C.</creator><creator>Di Ferrante, N.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TB</scope><scope>8FD</scope><scope>FR3</scope><scope>H8D</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>197910</creationdate><title>Amino aciduria in weightlessness</title><author>Leach, C.S. ; Rambaut, P.C. ; Di Ferrante, N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-1d77f2fb3ffc8a6bb85b1425e22d14b4192dfb8d40e68207f643feb172f725363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Adaptation, Physiological</topic><topic>Amino Acids - metabolism</topic><topic>Amino Acids - urine</topic><topic>Energy Metabolism - physiology</topic><topic>Humans</topic><topic>Hydroxylysine - analogs & derivatives</topic><topic>Hydroxylysine - metabolism</topic><topic>Hydroxylysine - urine</topic><topic>Hydroxyproline - metabolism</topic><topic>Hydroxyproline - urine</topic><topic>Male</topic><topic>Methylhistidines - metabolism</topic><topic>Methylhistidines - urine</topic><topic>Space Flight</topic><topic>Space life sciences</topic><topic>Weightlessness</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leach, C.S.</creatorcontrib><creatorcontrib>Rambaut, P.C.</creatorcontrib><creatorcontrib>Di Ferrante, N.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Acta astronautica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leach, C.S.</au><au>Rambaut, P.C.</au><au>Di Ferrante, N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Amino aciduria in weightlessness</atitle><jtitle>Acta astronautica</jtitle><addtitle>Acta Astronaut</addtitle><date>1979-10</date><risdate>1979</risdate><volume>6</volume><issue>10</issue><spage>1323</spage><epage>1333</epage><pages>1323-1333</pages><issn>0094-5765</issn><eissn>1879-2030</eissn><abstract>Urinary excretion of amino acids by the 9 Skylab crewmen was studied as an indicator of the metabolic effects caused by exposure to the space flight environment. Intake was consistent in quality and quantity throughout the 28, 59 and 84-day flights for each of the crewmen and complete collections were accomplished. The results indicated an increased excretion in most amino acids during the first month of flight which remained elevated in the second and third months but to a lesser extent. Additional indications of change in muscle and skeletal metabolism were observed. These results point to the desirability of obtaining additional indices of alterations in protein synthetic processes in conjunction with future space flights.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>11902175</pmid><doi>10.1016/0094-5765(79)90124-3</doi><tpages>11</tpages></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Adaptation, Physiological Amino Acids - metabolism Amino Acids - urine Energy Metabolism - physiology Humans Hydroxylysine - analogs & derivatives Hydroxylysine - metabolism Hydroxylysine - urine Hydroxyproline - metabolism Hydroxyproline - urine Male Methylhistidines - metabolism Methylhistidines - urine Space Flight Space life sciences Weightlessness |
title | Amino aciduria in weightlessness |
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