Motor neuron columnar fate imposed by sequential phases of Hox-c activity

The organization of neurons into columns is a prominent feature of central nervous system structure and function. In many regions of the central nervous system the grouping of neurons into columns links cell-body position to axonal trajectory, thus contributing to the establishment of topographic ne...

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Veröffentlicht in:	Nature 2003-10, Vol.425 (6961), p.926-933
Hauptverfasser:	Dasen, Jeremy S, Jessell, Thomas M, Liu, Jeh-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Body Patterning - drug effects Cell Differentiation - drug effects Central nervous system Chick Embryo DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Fibroblast Growth Factor 8 Fibroblast Growth Factors - genetics Fibroblast Growth Factors - metabolism Fibroblast Growth Factors - pharmacology Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental - drug effects Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Humanities and Social Sciences Mice Mitosis Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Motor Neurons - cytology Motor Neurons - metabolism multidisciplinary Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neurons Proteins RNA, Messenger - genetics RNA, Messenger - metabolism Science Science (multidisciplinary) Signal Transduction - drug effects Spinal cord Spinal Cord - cytology Spinal Cord - drug effects Spinal Cord - embryology Spinal Cord - metabolism Stem Cells - cytology Stem Cells - drug effects Stem Cells - metabolism Vertebrates: nervous system and sense organs
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