MHC class I alloantigen specificity of Ly-49 + IL-2-activated natural killer cells

THE molecular basis of target cell recognition by CD3 − natural killer (NK) cells is poorly understood, despite the ability of NK cells to lyse specific tumour cells 1,2 . In general, target cell major histocompatibility complex (MHC) class I antigen expression correlates with resistance to NK cell-...

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Veröffentlicht in:	Nature (London) 1992-07, Vol.358 (6381), p.66-70
Hauptverfasser:	Karlhofer, Franz M, Ribaudo, Randall K, Yokoyama, Wayne M
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Antigens Antigens, Ly - analysis Biological and medical sciences Cells, Cultured Cellular biology Cytotoxicity, Immunologic Fundamental and applied biological sciences. Psychology Fundamental immunology H-2 Antigens - genetics H-2 Antigens - immunology Humanities and Social Sciences Immunity, Cellular Immunobiology In Vitro Techniques Killer Cells, Lymphokine-Activated - immunology Killer Cells, Natural - immunology letter Lymphocyte Activation Lymphocyte Subsets - immunology Mice Molecules multidisciplinary Organs and cells involved in the immune response Peptides Science Science (multidisciplinary) Transfection
Online-Zugang:	Volltext
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