The pharmacokinetics of slow-release procainamide

Procainamide was given to 20 patients with normal renal function as an i.v. bolus of 500 mg followed by 1.0 or 1.5 g eight-hourly by mouth in the form of a slow release preparation (Durules). 97.6 +/- 27.1 (SD)% of the oral procainamide was absorbed, the absorption half life being 1.54 h. The elimin...

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Veröffentlicht in:	European journal of clinical pharmacology 1978-12, Vol.14 (4), p.261-265
Hauptverfasser:	Tilstone, W J, Lawson, D H, Campbell, W, Hutton, I, Lawrie, T D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Availability Delayed-Action Preparations Electrocardiography Half-Life Humans Kinetics Procainamide - administration & dosage Procainamide - metabolism
Online-Zugang:	Volltext
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