Oligodendrocyte Precursor Cells Reprogrammed to Become Multipotential CNS Stem Cells

During animal development, cells become progressively more restricted in the cell types to which they can give rise. In the central nervous system (CNS), for example, multipotential stem cells produce various kinds of specified precursors that divide a limited number of times before they terminally...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2000-09, Vol.289 (5485), p.1754-1757
Hauptverfasser:	Kondo, Toru, Raff, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy Animals Animals, Newborn Antibodies Astrocytes Astrocytes - chemistry Astrocytes - cytology Biological and medical sciences Blood Bone Morphogenetic Proteins - pharmacology Cell Culture Techniques Cell Differentiation Cell differentiation, maturation, development, hematopoiesis Cell physiology Cell research Cells, Cultured Cellular biology Central nervous system Culture Media Culture Media, Serum-Free Cultured cells Cytological research Fibroblast Growth Factor 2 - pharmacology Fundamental and applied biological sciences. Psychology Galactosylceramides - analysis Glial Fibrillary Acidic Protein - analysis Globular star clusters Glutamate Decarboxylase - biosynthesis Glutamate Decarboxylase - genetics Health aspects Individualized Instruction Isoenzymes - biosynthesis Isoenzymes - genetics Messenger RNA Molecular and cellular biology Nervous system Neurofilament Proteins - analysis Neurofilament Proteins - biosynthesis Neurons Neurons - chemistry Neurons - cytology Oligodendroglia Oligodendroglia - chemistry Oligodendroglia - cytology Optic Nerve - cytology Platelet-Derived Growth Factor - pharmacology Rats Stem cells Stem Cells - chemistry Stem Cells - cytology Thyroid Hormones - pharmacology
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