Ghrelin induces adiposity in rodents

The discovery of the peptide hormone ghrelin, an endogenous ligand for the growth hormone secretagogue (GHS) receptor 1 , 2 , yielded the surprising result 3 that the principal site of ghrelin synthesis is the stomach and not the hypothalamus. Although ghrelin is likely to regulate pituitary growth...

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Veröffentlicht in:	Nature (London) 2000-10, Vol.407 (6806), p.908-913
Hauptverfasser:	Tschöp, Matthias, Smiley, David L., Heiman, Mark L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - drug effects Adipose Tissue - metabolism Animals Biological and medical sciences Biology Body weight Circadian Rhythm Energy balance Energy Metabolism Fasting Feeding. Feeding behavior Food Fundamental and applied biological sciences. Psychology Ghrelin Growth Hormone - secretion Hormones Humanities and Social Sciences Hypothalamus - drug effects Hypothalamus - physiology Ingestion Injections, Intraventricular letter Male Mice multidisciplinary Peptide Hormones Peptides Peptides - administration & dosage Peptides - blood Peptides - physiology Rats Rats, Sprague-Dawley Receptors, Cell Surface - blood Receptors, Cell Surface - physiology Receptors, G-Protein-Coupled Receptors, Ghrelin Rodents Science Science (multidisciplinary) Vertebrates: anatomy and physiology, studies on body, several organs or systems Weight Weight Gain - drug effects Weight Gain - physiology
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