Crystal structure of a catalytic intermediate of the maltose transporter

The maltose uptake system of Escherichia coli is a well-characterized member of the ATP-binding cassette transporter superfamily. Here we present the 2.8-Å crystal structure of the intact maltose transporter in complex with the maltose-binding protein, maltose and ATP. This structure, stabilized by...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature 2007-11, Vol.450 (7169), p.515-521
Hauptverfasser:	Oldham, Michael L., Khare, Dheeraj, Quiocho, Florante A., Davidson, Amy L., Chen, Jue
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Adenosine Triphosphate - metabolism ATP ATP-Binding Cassette Transporters - chemistry ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Bacteriology Binding Sites Biological and medical sciences Carrier Proteins - chemistry Carrier Proteins - genetics Carrier Proteins - metabolism Catalysis Cell Membrane - metabolism CRYSTAL STRUCTURE Crystallization Crystallography, X-Ray Dimerization DIMERS Docks E coli ESCHERICHIA COLI Escherichia coli - chemistry Escherichia coli Proteins - chemistry Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Fundamental and applied biological sciences. Psychology Humanities and Social Sciences HYDROLYSIS LIPIDS MALTOSE Maltose - metabolism Maltose-Binding Proteins MATERIALS SCIENCE Microbiology Models, Biological Models, Molecular Molecular biology Monosaccharide Transport Proteins - chemistry Monosaccharide Transport Proteins - genetics Monosaccharide Transport Proteins - metabolism multidisciplinary Multiprotein Complexes - chemistry Multiprotein Complexes - genetics Multiprotein Complexes - metabolism Mutation Mutation - genetics MUTATIONS Permeability, membrane transport, intracellular transport Protein Conformation PROTEINS SACCHAROSE Science Science (multidisciplinary) SOLUTES Solvents Sugar TRANSLOCATION TRANSPORT
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!