Aldoximes: Active‐Site Probes of Alcohol Dehydrogenases

The oximes of aliphatic aldehydes inhibit horse liver and yeast alcohol dehydrogenase. The pattern of inhibition of these enzymes by the oximes reflects their substrate specificity. For example, acetaldoxime is a more effective inhibitor of the yeast enzyme than butyraldoxime (K1 0.06 mM and 2 mM re...

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Veröffentlicht in:	European journal of biochemistry 1982-09, Vol.126 (3), p.523-529
Hauptverfasser:	SIGMAN, David S., FROLICH, Marianne, ANDERSON, Robert E.
Format:	Artikel
Sprache:	eng
Schlagworte:	alcohol dehydrogenase Alcohol Oxidoreductases - antagonists & inhibitors aldoxime Animals Binding Sites - drug effects Horses liver Liver - enzymology Oximes - pharmacology Saccharomyces cerevisiae
Online-Zugang:	Volltext
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