Salmon calcitonin in lizard brain: a possible neuroendocrine transmitter

Calcitonin is a polypeptide which until recently was thought to be concerned primarily with the control of body calcium. Recent studies carried out with radioimmunoassay have demonstrated the presence of this peptide in brain and we have carried out an immunohistochemical study showing the presence...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Brain research 1982-11, Vol.251 (2), p.371-373
Hauptverfasser: MacInnes, D.G., Laszlo, I., MacIntyre, I., Fink, G.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 373
container_issue 2
container_start_page 371
container_title Brain research
container_volume 251
creator MacInnes, D.G.
Laszlo, I.
MacIntyre, I.
Fink, G.
description Calcitonin is a polypeptide which until recently was thought to be concerned primarily with the control of body calcium. Recent studies carried out with radioimmunoassay have demonstrated the presence of this peptide in brain and we have carried out an immunohistochemical study showing the presence of high concentrations of calcitonin in the nerve varicosities and terminals of the hypothalamus and in particular the median eminence of the lizard Lacertus muralis. The distribution of this calcitonin, which cross-reacted with anti-salmon calcitonin, suggests that this polypeptide and/or its flanking peptides may function as a neuroendocrine neurotransmitter.
doi_str_mv 10.1016/0006-8993(82)90756-9
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_74290329</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0006899382907569</els_id><sourcerecordid>74290329</sourcerecordid><originalsourceid>FETCH-LOGICAL-c388t-6c2f3c4b3d423930d387ea195759e65be3c42f6a30a4e9b62428b0d287c1f8313</originalsourceid><addsrcrecordid>eNqFkEtLAzEUhYMotVb_gcKsRBejecwjcSFIUSsUXKjrkEnuQGQmqclU0F9vxpYuFS6Eyzk5yfkQOiX4imBSXWOMq5wLwS44vRS4Lqtc7KEp4TXNK1rgfTTdWQ7RUYzvaWVM4Ama1IQJxtgULV5U13uXadVpO3hnXZams98qmKwJyrqbTGUrH6NtOsgcrIMHZ7wO1kE2BOVib4cBwjE6aFUX4WR7ztDbw_3rfJEvnx-f5nfLXDPOh7zStGW6aJgpaPoCNozXoIgo61JAVTaQRNpWimFVgGhSD8obbCivNWk5I2yGzje5q-A_1hAH2duooeuUA7-Osi6owIyKf42kLIuaEZ6MxcaoQ6oZoJWrYHsVviTBciQtR4xyxCg5lb-k5Zh_ts1fNz2Y3aUt2qTfbnRIND4tBBm1BafB2AB6kMbbvx_4AcInjJM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15547318</pqid></control><display><type>article</type><title>Salmon calcitonin in lizard brain: a possible neuroendocrine transmitter</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>MacInnes, D.G. ; Laszlo, I. ; MacIntyre, I. ; Fink, G.</creator><creatorcontrib>MacInnes, D.G. ; Laszlo, I. ; MacIntyre, I. ; Fink, G.</creatorcontrib><description>Calcitonin is a polypeptide which until recently was thought to be concerned primarily with the control of body calcium. Recent studies carried out with radioimmunoassay have demonstrated the presence of this peptide in brain and we have carried out an immunohistochemical study showing the presence of high concentrations of calcitonin in the nerve varicosities and terminals of the hypothalamus and in particular the median eminence of the lizard Lacertus muralis. The distribution of this calcitonin, which cross-reacted with anti-salmon calcitonin, suggests that this polypeptide and/or its flanking peptides may function as a neuroendocrine neurotransmitter.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0006-8993(82)90756-9</identifier><identifier>PMID: 7139333</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Brain - physiology ; Brain Chemistry ; Calcitonin - analysis ; hypothalamus ; Hypothalamus - analysis ; Lacerta muralis ; Lizards ; median eminence ; Median Eminence - analysis ; neurotransmitter ; Salmon ; salmon calcitonin ; Species Specificity</subject><ispartof>Brain research, 1982-11, Vol.251 (2), p.371-373</ispartof><rights>1982 Elsevier Biomedical Press, Amsterdam</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-6c2f3c4b3d423930d387ea195759e65be3c42f6a30a4e9b62428b0d287c1f8313</citedby><cites>FETCH-LOGICAL-c388t-6c2f3c4b3d423930d387ea195759e65be3c42f6a30a4e9b62428b0d287c1f8313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0006899382907569$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7139333$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MacInnes, D.G.</creatorcontrib><creatorcontrib>Laszlo, I.</creatorcontrib><creatorcontrib>MacIntyre, I.</creatorcontrib><creatorcontrib>Fink, G.</creatorcontrib><title>Salmon calcitonin in lizard brain: a possible neuroendocrine transmitter</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>Calcitonin is a polypeptide which until recently was thought to be concerned primarily with the control of body calcium. Recent studies carried out with radioimmunoassay have demonstrated the presence of this peptide in brain and we have carried out an immunohistochemical study showing the presence of high concentrations of calcitonin in the nerve varicosities and terminals of the hypothalamus and in particular the median eminence of the lizard Lacertus muralis. The distribution of this calcitonin, which cross-reacted with anti-salmon calcitonin, suggests that this polypeptide and/or its flanking peptides may function as a neuroendocrine neurotransmitter.</description><subject>Animals</subject><subject>Brain - physiology</subject><subject>Brain Chemistry</subject><subject>Calcitonin - analysis</subject><subject>hypothalamus</subject><subject>Hypothalamus - analysis</subject><subject>Lacerta muralis</subject><subject>Lizards</subject><subject>median eminence</subject><subject>Median Eminence - analysis</subject><subject>neurotransmitter</subject><subject>Salmon</subject><subject>salmon calcitonin</subject><subject>Species Specificity</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMotVb_gcKsRBejecwjcSFIUSsUXKjrkEnuQGQmqclU0F9vxpYuFS6Eyzk5yfkQOiX4imBSXWOMq5wLwS44vRS4Lqtc7KEp4TXNK1rgfTTdWQ7RUYzvaWVM4Ama1IQJxtgULV5U13uXadVpO3hnXZams98qmKwJyrqbTGUrH6NtOsgcrIMHZ7wO1kE2BOVib4cBwjE6aFUX4WR7ztDbw_3rfJEvnx-f5nfLXDPOh7zStGW6aJgpaPoCNozXoIgo61JAVTaQRNpWimFVgGhSD8obbCivNWk5I2yGzje5q-A_1hAH2duooeuUA7-Osi6owIyKf42kLIuaEZ6MxcaoQ6oZoJWrYHsVviTBciQtR4xyxCg5lb-k5Zh_ts1fNz2Y3aUt2qTfbnRIND4tBBm1BafB2AB6kMbbvx_4AcInjJM</recordid><startdate>19821118</startdate><enddate>19821118</enddate><creator>MacInnes, D.G.</creator><creator>Laszlo, I.</creator><creator>MacIntyre, I.</creator><creator>Fink, G.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19821118</creationdate><title>Salmon calcitonin in lizard brain: a possible neuroendocrine transmitter</title><author>MacInnes, D.G. ; Laszlo, I. ; MacIntyre, I. ; Fink, G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-6c2f3c4b3d423930d387ea195759e65be3c42f6a30a4e9b62428b0d287c1f8313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Animals</topic><topic>Brain - physiology</topic><topic>Brain Chemistry</topic><topic>Calcitonin - analysis</topic><topic>hypothalamus</topic><topic>Hypothalamus - analysis</topic><topic>Lacerta muralis</topic><topic>Lizards</topic><topic>median eminence</topic><topic>Median Eminence - analysis</topic><topic>neurotransmitter</topic><topic>Salmon</topic><topic>salmon calcitonin</topic><topic>Species Specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MacInnes, D.G.</creatorcontrib><creatorcontrib>Laszlo, I.</creatorcontrib><creatorcontrib>MacIntyre, I.</creatorcontrib><creatorcontrib>Fink, G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MacInnes, D.G.</au><au>Laszlo, I.</au><au>MacIntyre, I.</au><au>Fink, G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Salmon calcitonin in lizard brain: a possible neuroendocrine transmitter</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1982-11-18</date><risdate>1982</risdate><volume>251</volume><issue>2</issue><spage>371</spage><epage>373</epage><pages>371-373</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><abstract>Calcitonin is a polypeptide which until recently was thought to be concerned primarily with the control of body calcium. Recent studies carried out with radioimmunoassay have demonstrated the presence of this peptide in brain and we have carried out an immunohistochemical study showing the presence of high concentrations of calcitonin in the nerve varicosities and terminals of the hypothalamus and in particular the median eminence of the lizard Lacertus muralis. The distribution of this calcitonin, which cross-reacted with anti-salmon calcitonin, suggests that this polypeptide and/or its flanking peptides may function as a neuroendocrine neurotransmitter.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>7139333</pmid><doi>10.1016/0006-8993(82)90756-9</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0006-8993
ispartof Brain research, 1982-11, Vol.251 (2), p.371-373
issn 0006-8993
1872-6240
language eng
recordid cdi_proquest_miscellaneous_74290329
source MEDLINE; Elsevier ScienceDirect Journals
subjects Animals
Brain - physiology
Brain Chemistry
Calcitonin - analysis
hypothalamus
Hypothalamus - analysis
Lacerta muralis
Lizards
median eminence
Median Eminence - analysis
neurotransmitter
Salmon
salmon calcitonin
Species Specificity
title Salmon calcitonin in lizard brain: a possible neuroendocrine transmitter
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T13%3A43%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Salmon%20calcitonin%20in%20lizard%20brain:%20a%20possible%20neuroendocrine%20transmitter&rft.jtitle=Brain%20research&rft.au=MacInnes,%20D.G.&rft.date=1982-11-18&rft.volume=251&rft.issue=2&rft.spage=371&rft.epage=373&rft.pages=371-373&rft.issn=0006-8993&rft.eissn=1872-6240&rft_id=info:doi/10.1016/0006-8993(82)90756-9&rft_dat=%3Cproquest_cross%3E74290329%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15547318&rft_id=info:pmid/7139333&rft_els_id=0006899382907569&rfr_iscdi=true