CIRCADIAN RHYTHMS OF BLOOD PRESSURE AND PRESSOR HORMONES IN NORMAL AND HYPERTENSIVE PREGNANCY

SUMMARY 1.Circadian patterns of blood pressure and pressor hormones were studied in late pregnancy in ten normotensive women and twenty‐one hypertensives. 2.Plasma renin activity, angiotensin II and free adrenaline and noradrenaline levels were highest at 0900 h in normotensives and uncomplicated hy...

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Veröffentlicht in:Clinical and experimental pharmacology & physiology 1982-06, Vol.9 (3), p.321-326
Hauptverfasser: Beilin, Lawrence J., Deacon, Jane, Michael, Con A., Vandongen, Robert, Lalor, Claire M., Barden, Ann E., Davidson, Lisa
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container_end_page 326
container_issue 3
container_start_page 321
container_title Clinical and experimental pharmacology & physiology
container_volume 9
creator Beilin, Lawrence J.
Deacon, Jane
Michael, Con A.
Vandongen, Robert
Lalor, Claire M.
Barden, Ann E.
Davidson, Lisa
description SUMMARY 1.Circadian patterns of blood pressure and pressor hormones were studied in late pregnancy in ten normotensive women and twenty‐one hypertensives. 2.Plasma renin activity, angiotensin II and free adrenaline and noradrenaline levels were highest at 0900 h in normotensives and uncomplicated hypertensives. Catecholamine sulphate levels were lowest at 0900 h. 3. In eight pre‐eclamptic hypertensives, plasma renin activity, and angiotensin II were suppressed. 4. Adrenaline sulphate levels were raised in hypertensives. 5. Four pre‐eclamptics with noctural hypertension had the highest blood pressures; their diurnal rhythm for noradrenaline sulphate was reversed but they showed no consistent pattern of pressor hormones. However failure of angiotensin II, adrenaline or noradrenaline to fall at night in subjects with increased vascular reactivity could contribute to their nocturnal hypertension.
doi_str_mv 10.1111/j.1440-1681.1982.tb00814.x
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Catecholamine sulphate levels were lowest at 0900 h. 3. In eight pre‐eclamptic hypertensives, plasma renin activity, and angiotensin II were suppressed. 4. Adrenaline sulphate levels were raised in hypertensives. 5. Four pre‐eclamptics with noctural hypertension had the highest blood pressures; their diurnal rhythm for noradrenaline sulphate was reversed but they showed no consistent pattern of pressor hormones. 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Catecholamine sulphate levels were lowest at 0900 h. 3. In eight pre‐eclamptic hypertensives, plasma renin activity, and angiotensin II were suppressed. 4. Adrenaline sulphate levels were raised in hypertensives. 5. Four pre‐eclamptics with noctural hypertension had the highest blood pressures; their diurnal rhythm for noradrenaline sulphate was reversed but they showed no consistent pattern of pressor hormones. However failure of angiotensin II, adrenaline or noradrenaline to fall at night in subjects with increased vascular reactivity could contribute to their nocturnal hypertension.</description><subject>adrenaline</subject><subject>adrenaline, angiotensin II, catecholamines, hypertension, noradrenaline, pre‐eclampsia, pregnancy, renin</subject><subject>Adult</subject><subject>angiotensin II</subject><subject>Angiotensin II - blood</subject><subject>Blood Pressure</subject><subject>catecholamines</subject><subject>Circadian Rhythm</subject><subject>Epinephrine - blood</subject><subject>Female</subject><subject>Hormones - blood</subject><subject>Humans</subject><subject>hypertension</subject><subject>Hypertension - blood</subject><subject>Hypertension - physiopathology</subject><subject>noradrenaline</subject><subject>Norepinephrine - blood</subject><subject>pre-eclampsia</subject><subject>Pre-Eclampsia - blood</subject><subject>Pre-Eclampsia - physiopathology</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Cardiovascular</subject><subject>renin</subject><subject>Renin - blood</subject><issn>0305-1870</issn><issn>1440-1681</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF1r2zAUhkVZ6bK0P2FgdrE7u0cftpRdDDzHtT1SOdhJRy6G8IcCyZIlsxKa_vvaicn9xAHp8L7nPehB6AsGB7fnce1gxsDGnsAOHgniHEoAgZlzukGDq_QBDYCCa2PB4SP6ZMwaAFzw6B2687jLMB8N0O8gyQJ_nPjSyuLFLH7OrfTJ-jFJ07E1zcI8n2eh5cu-STMrTrPnVIa5lUhLtm9_cpbjxTTMZqHMk5ew80bSl8HiHt0ui43RD_09RPOncBbE9iSNksCf2BUDju2y9kTpFkLDiGvhCsF0zaAkFdOeAI8XtKpKOgJOOSGctlUTXAleF5hUmmA6RF8vuftm9--ozUFtV6bSm03xV--ORnFGhOcBaY3fLsaq2RnT6KXaN6tt0bwpDKpjq9aqA6g6gKpjq3q26tQOf-63HMutrq-jPcxW_37RX1cb_fYfySoIp_T8DfsSsDIHfboGFM2fdgflrvolI_UzyqcMR4ES9B1KR48r</recordid><startdate>198206</startdate><enddate>198206</enddate><creator>Beilin, Lawrence J.</creator><creator>Deacon, Jane</creator><creator>Michael, Con A.</creator><creator>Vandongen, Robert</creator><creator>Lalor, Claire M.</creator><creator>Barden, Ann E.</creator><creator>Davidson, Lisa</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198206</creationdate><title>CIRCADIAN RHYTHMS OF BLOOD PRESSURE AND PRESSOR HORMONES IN NORMAL AND HYPERTENSIVE PREGNANCY</title><author>Beilin, Lawrence J. ; Deacon, Jane ; Michael, Con A. ; Vandongen, Robert ; Lalor, Claire M. ; Barden, Ann E. ; Davidson, Lisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4071-bd68b5a8e097e85884ed40b2c4e68067a3ccb3907372273273d21c87da12ce213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>adrenaline</topic><topic>adrenaline, angiotensin II, catecholamines, hypertension, noradrenaline, pre‐eclampsia, pregnancy, renin</topic><topic>Adult</topic><topic>angiotensin II</topic><topic>Angiotensin II - blood</topic><topic>Blood Pressure</topic><topic>catecholamines</topic><topic>Circadian Rhythm</topic><topic>Epinephrine - blood</topic><topic>Female</topic><topic>Hormones - blood</topic><topic>Humans</topic><topic>hypertension</topic><topic>Hypertension - blood</topic><topic>Hypertension - physiopathology</topic><topic>noradrenaline</topic><topic>Norepinephrine - blood</topic><topic>pre-eclampsia</topic><topic>Pre-Eclampsia - blood</topic><topic>Pre-Eclampsia - physiopathology</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Cardiovascular</topic><topic>renin</topic><topic>Renin - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Beilin, Lawrence J.</creatorcontrib><creatorcontrib>Deacon, Jane</creatorcontrib><creatorcontrib>Michael, Con A.</creatorcontrib><creatorcontrib>Vandongen, Robert</creatorcontrib><creatorcontrib>Lalor, Claire M.</creatorcontrib><creatorcontrib>Barden, Ann E.</creatorcontrib><creatorcontrib>Davidson, Lisa</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental pharmacology &amp; physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Beilin, Lawrence J.</au><au>Deacon, Jane</au><au>Michael, Con A.</au><au>Vandongen, Robert</au><au>Lalor, Claire M.</au><au>Barden, Ann E.</au><au>Davidson, Lisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CIRCADIAN RHYTHMS OF BLOOD PRESSURE AND PRESSOR HORMONES IN NORMAL AND HYPERTENSIVE PREGNANCY</atitle><jtitle>Clinical and experimental pharmacology &amp; physiology</jtitle><addtitle>Clin Exp Pharmacol Physiol</addtitle><date>1982-06</date><risdate>1982</risdate><volume>9</volume><issue>3</issue><spage>321</spage><epage>326</epage><pages>321-326</pages><issn>0305-1870</issn><eissn>1440-1681</eissn><abstract>SUMMARY 1.Circadian patterns of blood pressure and pressor hormones were studied in late pregnancy in ten normotensive women and twenty‐one hypertensives. 2.Plasma renin activity, angiotensin II and free adrenaline and noradrenaline levels were highest at 0900 h in normotensives and uncomplicated hypertensives. Catecholamine sulphate levels were lowest at 0900 h. 3. In eight pre‐eclamptic hypertensives, plasma renin activity, and angiotensin II were suppressed. 4. Adrenaline sulphate levels were raised in hypertensives. 5. Four pre‐eclamptics with noctural hypertension had the highest blood pressures; their diurnal rhythm for noradrenaline sulphate was reversed but they showed no consistent pattern of pressor hormones. However failure of angiotensin II, adrenaline or noradrenaline to fall at night in subjects with increased vascular reactivity could contribute to their nocturnal hypertension.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>6754179</pmid><doi>10.1111/j.1440-1681.1982.tb00814.x</doi><tpages>6</tpages></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects adrenaline
adrenaline, angiotensin II, catecholamines, hypertension, noradrenaline, pre‐eclampsia, pregnancy, renin
Adult
angiotensin II
Angiotensin II - blood
Blood Pressure
catecholamines
Circadian Rhythm
Epinephrine - blood
Female
Hormones - blood
Humans
hypertension
Hypertension - blood
Hypertension - physiopathology
noradrenaline
Norepinephrine - blood
pre-eclampsia
Pre-Eclampsia - blood
Pre-Eclampsia - physiopathology
Pregnancy
Pregnancy Complications, Cardiovascular
renin
Renin - blood
title CIRCADIAN RHYTHMS OF BLOOD PRESSURE AND PRESSOR HORMONES IN NORMAL AND HYPERTENSIVE PREGNANCY
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