Pumpkin seed inhibitor of human factor XIIa (activated Hageman factor) and bovine trypsin

A strong inhibitor of human Hageman factor fragment (HFf, beta-factor XIIa) and bovine trypsin was isolated from pumpkin (Cucurbita maxima) seed extracts by acetone fractionation, by chromatography on columns of diethyl-aminoethylcellulose and carboxylmethyl-Sephadex C-25, and by Sephadex G-50 gel f...

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Veröffentlicht in:	Biochemistry (Easton) 1982-08, Vol.21 (16), p.3741-3746
Hauptverfasser:	Hojima, Yoshio, Pierce, Jack V, Pisano, John J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - analysis Animals Cattle Chymotrypsin - metabolism Factor V - antagonists & inhibitors Factor Va Factor XII - antagonists & inhibitors Fibrinolysin - antagonists & inhibitors Isoelectric Point Kallikreins - metabolism Plant Extracts - pharmacology Seeds - analysis Thrombin - metabolism Trypsin Inhibitors - isolation & purification
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