Intra-articular loose bodies regarded as organ cultures in vivo
A study of the changes which occur in the intra-articular loose bodies which contain hyaline cartilage, showed the chondrocytes to be very versatile. To effect the transformation of a fractured portion of the articular surface from an angular to a rounded body, peripheral chondrocytes lyse the surro...
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| Veröffentlicht in: | The Journal of pathology 1978-07, Vol.125 (3), p.163-169 |
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| container_title | The Journal of pathology |
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| creator | Barrie, H. J. |
| description | A study of the changes which occur in the intra-articular loose bodies which contain hyaline cartilage, showed the chondrocytes to be very versatile. To effect the transformation of a fractured portion of the articular surface from an angular to a rounded body, peripheral chondrocytes lyse the surrounding glycans and revert to fibroblasts before proliferating and forming fibrocartilage. The central chondrocytes show a wide variety of changes which may mask the original structure of the hyaline cartilage. Remodelling can occur by the formation of osteoclasts. Analogies are drawn between the behaviour of chondrocytes in culture and in some pathologic processes. |
| doi_str_mv | 10.1002/path.1711250307 |
| format | Article |
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J.</creator><creatorcontrib>Barrie, H. J.</creatorcontrib><description>A study of the changes which occur in the intra-articular loose bodies which contain hyaline cartilage, showed the chondrocytes to be very versatile. To effect the transformation of a fractured portion of the articular surface from an angular to a rounded body, peripheral chondrocytes lyse the surrounding glycans and revert to fibroblasts before proliferating and forming fibrocartilage. The central chondrocytes show a wide variety of changes which may mask the original structure of the hyaline cartilage. Remodelling can occur by the formation of osteoclasts. 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J.</creatorcontrib><title>Intra-articular loose bodies regarded as organ cultures in vivo</title><title>The Journal of pathology</title><addtitle>J. Pathol</addtitle><description>A study of the changes which occur in the intra-articular loose bodies which contain hyaline cartilage, showed the chondrocytes to be very versatile. To effect the transformation of a fractured portion of the articular surface from an angular to a rounded body, peripheral chondrocytes lyse the surrounding glycans and revert to fibroblasts before proliferating and forming fibrocartilage. The central chondrocytes show a wide variety of changes which may mask the original structure of the hyaline cartilage. Remodelling can occur by the formation of osteoclasts. Analogies are drawn between the behaviour of chondrocytes in culture and in some pathologic processes.</description><subject>Bone Resorption - pathology</subject><subject>Cartilage, Articular - pathology</subject><subject>Cell Division</subject><subject>Humans</subject><subject>Joint Diseases - pathology</subject><subject>Knee Joint - pathology</subject><subject>Organ Culture Techniques</subject><subject>Osteoclasts - pathology</subject><issn>0022-3417</issn><issn>1096-9896</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtPwkAUhSfGF6JrNy66cleYR9vpxIUhoEAEdYFxOZnOA6uFwZkW5d9bUoJx5eouzne-mxwALhHsIAhxdyXKtw6iCOEYEkgPQAtBloQsZckhaNUEDkmE6Ck48_4dQshYHJ-AY4oxYWkL3I6XpROhcGUuq0K4oLDW6yCzKtc-cHounNIqED6wbi6WQQ2VlaujfBms87U9B0dGFF5f7G4bvNzfzfqjcPI0HPd7k1BiltCQGgqxyuqvNEpYxJTSRBhlMklSJQVEhCUkIgomKKbSpBIphpNMGaxVTAwhbXDdeFfOflbal3yRe6mLQiy1rTynEaaExKgGuw0onfXeacNXLl8It-EI8u1ifLsY_12sblzt1FW20GrPNxPV8U0Tf-WF3vxn48-92eiPPGzauS_1974t3AdPKKExf30c8kE8mw77D1M-ID-obIeP</recordid><startdate>197807</startdate><enddate>197807</enddate><creator>Barrie, H. 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J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2967-7f702db722746949dde3afdfbc38dca01396343d06157cf8c1d926bdf2ed53f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Bone Resorption - pathology</topic><topic>Cartilage, Articular - pathology</topic><topic>Cell Division</topic><topic>Humans</topic><topic>Joint Diseases - pathology</topic><topic>Knee Joint - pathology</topic><topic>Organ Culture Techniques</topic><topic>Osteoclasts - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barrie, H. 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Pathol</addtitle><date>1978-07</date><risdate>1978</risdate><volume>125</volume><issue>3</issue><spage>163</spage><epage>169</epage><pages>163-169</pages><issn>0022-3417</issn><eissn>1096-9896</eissn><abstract>A study of the changes which occur in the intra-articular loose bodies which contain hyaline cartilage, showed the chondrocytes to be very versatile. To effect the transformation of a fractured portion of the articular surface from an angular to a rounded body, peripheral chondrocytes lyse the surrounding glycans and revert to fibroblasts before proliferating and forming fibrocartilage. The central chondrocytes show a wide variety of changes which may mask the original structure of the hyaline cartilage. Remodelling can occur by the formation of osteoclasts. Analogies are drawn between the behaviour of chondrocytes in culture and in some pathologic processes.</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>722398</pmid><doi>10.1002/path.1711250307</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3417 |
| ispartof | The Journal of pathology, 1978-07, Vol.125 (3), p.163-169 |
| issn | 0022-3417 1096-9896 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74273351 |
| source | Wiley-Blackwell Journals; MEDLINE |
| subjects | Bone Resorption - pathology Cartilage, Articular - pathology Cell Division Humans Joint Diseases - pathology Knee Joint - pathology Organ Culture Techniques Osteoclasts - pathology |
| title | Intra-articular loose bodies regarded as organ cultures in vivo |
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