Early-onset major depressive disorder in men is associated with childlessness
Abstract Methods The self-reported number of children was compared for men and women from the National Epidemiologic Survey of Alcoholism and Related Conditions Survey (NESARC). Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disord...
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description | Abstract Methods The self-reported number of children was compared for men and women from the National Epidemiologic Survey of Alcoholism and Related Conditions Survey (NESARC). Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disorder. The effect of age, gender, marriage and diagnostic status on number of children was completed using multivariate analyses. Results Men with a history of major depressive disorder but not bipolar disorder reported higher rates of childlessness and lower mean number of children. This reduced number of children was related to an early age of onset of MDD. Thirty percent of men with an age of onset of MDD before 22 were childless compared to only 18.9% of men without an axis I disorder (Odds ratio = 1.82, 95% CI = 1.45–2.27). No effect of mood disorder on number of children was found in women with major depression or bipolar disorder. Discussion This study suggests that an early age of onset of major depressive disorder contributes to childlessness in men. |
doi_str_mv | 10.1016/j.jad.2009.10.024 |
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Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disorder. The effect of age, gender, marriage and diagnostic status on number of children was completed using multivariate analyses. Results Men with a history of major depressive disorder but not bipolar disorder reported higher rates of childlessness and lower mean number of children. This reduced number of children was related to an early age of onset of MDD. Thirty percent of men with an age of onset of MDD before 22 were childless compared to only 18.9% of men without an axis I disorder (Odds ratio = 1.82, 95% CI = 1.45–2.27). No effect of mood disorder on number of children was found in women with major depression or bipolar disorder. Discussion This study suggests that an early age of onset of major depressive disorder contributes to childlessness in men.</description><identifier>ISSN: 0165-0327</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/j.jad.2009.10.024</identifier><identifier>PMID: 19931182</identifier><identifier>CODEN: JADID7</identifier><language>eng</language><publisher>Oxford: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Adult and adolescent clinical studies ; Age of Onset ; Biological and medical sciences ; Bipolar affective disorder ; Bipolar disorder ; Bipolar Disorder - diagnosis ; Bipolar Disorder - epidemiology ; Bipolar Disorder - psychology ; Bipolar disorders ; Childlessness ; Children ; Depression ; Depressive Disorder, Major - diagnosis ; Depressive Disorder, Major - epidemiology ; Depressive Disorder, Major - psychology ; Depressive personality disorders ; Family Characteristics ; Female ; Health Surveys ; Humans ; Male ; Medical sciences ; Men ; Middle Aged ; Mood disorders ; Odds Ratio ; Psychiatry ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Reproductive Behavior - psychology ; Reproductive Behavior - statistics & numerical data ; Sex Factors ; United States ; Young Adult</subject><ispartof>Journal of affective disorders, 2010-07, Vol.124 (1), p.187-190</ispartof><rights>Elsevier B.V.</rights><rights>2009 Elsevier B.V.</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c469t-d8320038d82cb3c3a805f4bca2b3960079e65152a114effd105bbf2dad48b3483</citedby><cites>FETCH-LOGICAL-c469t-d8320038d82cb3c3a805f4bca2b3960079e65152a114effd105bbf2dad48b3483</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jad.2009.10.024$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,31000,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22838360$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19931182$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yates, William R</creatorcontrib><creatorcontrib>Meller, William H</creatorcontrib><creatorcontrib>Lund, Brian C</creatorcontrib><creatorcontrib>Thurber, Steve</creatorcontrib><creatorcontrib>Grambsch, Patricia L</creatorcontrib><title>Early-onset major depressive disorder in men is associated with childlessness</title><title>Journal of affective disorders</title><addtitle>J Affect Disord</addtitle><description>Abstract Methods The self-reported number of children was compared for men and women from the National Epidemiologic Survey of Alcoholism and Related Conditions Survey (NESARC). Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disorder. The effect of age, gender, marriage and diagnostic status on number of children was completed using multivariate analyses. Results Men with a history of major depressive disorder but not bipolar disorder reported higher rates of childlessness and lower mean number of children. This reduced number of children was related to an early age of onset of MDD. Thirty percent of men with an age of onset of MDD before 22 were childless compared to only 18.9% of men without an axis I disorder (Odds ratio = 1.82, 95% CI = 1.45–2.27). No effect of mood disorder on number of children was found in women with major depression or bipolar disorder. Discussion This study suggests that an early age of onset of major depressive disorder contributes to childlessness in men.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Age of Onset</subject><subject>Biological and medical sciences</subject><subject>Bipolar affective disorder</subject><subject>Bipolar disorder</subject><subject>Bipolar Disorder - diagnosis</subject><subject>Bipolar Disorder - epidemiology</subject><subject>Bipolar Disorder - psychology</subject><subject>Bipolar disorders</subject><subject>Childlessness</subject><subject>Children</subject><subject>Depression</subject><subject>Depressive Disorder, Major - diagnosis</subject><subject>Depressive Disorder, Major - epidemiology</subject><subject>Depressive Disorder, Major - psychology</subject><subject>Depressive personality disorders</subject><subject>Family Characteristics</subject><subject>Female</subject><subject>Health Surveys</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Men</subject><subject>Middle Aged</subject><subject>Mood disorders</subject><subject>Odds Ratio</subject><subject>Psychiatry</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Reproductive Behavior - psychology</subject><subject>Reproductive Behavior - statistics & numerical data</subject><subject>Sex Factors</subject><subject>United States</subject><subject>Young Adult</subject><issn>0165-0327</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqFkk2LFDEQhoMo7rj6A7xILrKnHisf3Z1GEJZl1YUVD-o5pJNqNm1_jKmeXebfm2YGBQ_uIYSE560UT4qx1wK2AkT1rt_2LmwlQJPPW5D6CduIslaFLEX9lG0yUxagZH3GXhD1AFA1NTxnZ6JplBBGbtiXa5eGQzFPhAsfXT8nHnCXkCjeIw-R5hQw8TjxESceiTui2Ue3YOAPcbnj_i4OYcj8lNdL9qxzA-Gr037Ofny8_n71ubj9-unm6vK28LpqliIYlZtWJhjpW-WVM1B2uvVOtqqpAOoGq1KU0gmhseuCgLJtOxlc0KZV2qhzdnGsu0vzrz3SYsdIHofBTTjvydZa1rI2pXicVBpkVVU6k-JI-jQTJezsLsXRpYMVYFfdtrdZt111r1dZd868OVXftyOGv4mT3wy8PQGOvBu65CYf6Q8npVFGVZC590cOs7X7iMmSjzh5DDGhX2yY43_b-PBP2g9xivnBn3hA6ud9mvJ3WGFJWrDf1rlYxwIaAG20Vr8BrTqxOA</recordid><startdate>20100701</startdate><enddate>20100701</enddate><creator>Yates, William R</creator><creator>Meller, William H</creator><creator>Lund, Brian C</creator><creator>Thurber, Steve</creator><creator>Grambsch, Patricia L</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QJ</scope></search><sort><creationdate>20100701</creationdate><title>Early-onset major depressive disorder in men is associated with childlessness</title><author>Yates, William R ; Meller, William H ; Lund, Brian C ; Thurber, Steve ; Grambsch, Patricia L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c469t-d8320038d82cb3c3a805f4bca2b3960079e65152a114effd105bbf2dad48b3483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Age of Onset</topic><topic>Biological and medical sciences</topic><topic>Bipolar affective disorder</topic><topic>Bipolar disorder</topic><topic>Bipolar Disorder - diagnosis</topic><topic>Bipolar Disorder - epidemiology</topic><topic>Bipolar Disorder - psychology</topic><topic>Bipolar disorders</topic><topic>Childlessness</topic><topic>Children</topic><topic>Depression</topic><topic>Depressive Disorder, Major - diagnosis</topic><topic>Depressive Disorder, Major - epidemiology</topic><topic>Depressive Disorder, Major - psychology</topic><topic>Depressive personality disorders</topic><topic>Family Characteristics</topic><topic>Female</topic><topic>Health Surveys</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Men</topic><topic>Middle Aged</topic><topic>Mood disorders</topic><topic>Odds Ratio</topic><topic>Psychiatry</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Reproductive Behavior - psychology</topic><topic>Reproductive Behavior - statistics & numerical data</topic><topic>Sex Factors</topic><topic>United States</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yates, William R</creatorcontrib><creatorcontrib>Meller, William H</creatorcontrib><creatorcontrib>Lund, Brian C</creatorcontrib><creatorcontrib>Thurber, Steve</creatorcontrib><creatorcontrib>Grambsch, Patricia L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yates, William R</au><au>Meller, William H</au><au>Lund, Brian C</au><au>Thurber, Steve</au><au>Grambsch, Patricia L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early-onset major depressive disorder in men is associated with childlessness</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>2010-07-01</date><risdate>2010</risdate><volume>124</volume><issue>1</issue><spage>187</spage><epage>190</epage><pages>187-190</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><coden>JADID7</coden><abstract>Abstract Methods The self-reported number of children was compared for men and women from the National Epidemiologic Survey of Alcoholism and Related Conditions Survey (NESARC). Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disorder. The effect of age, gender, marriage and diagnostic status on number of children was completed using multivariate analyses. Results Men with a history of major depressive disorder but not bipolar disorder reported higher rates of childlessness and lower mean number of children. This reduced number of children was related to an early age of onset of MDD. Thirty percent of men with an age of onset of MDD before 22 were childless compared to only 18.9% of men without an axis I disorder (Odds ratio = 1.82, 95% CI = 1.45–2.27). No effect of mood disorder on number of children was found in women with major depression or bipolar disorder. Discussion This study suggests that an early age of onset of major depressive disorder contributes to childlessness in men.</abstract><cop>Oxford</cop><pub>Elsevier B.V</pub><pmid>19931182</pmid><doi>10.1016/j.jad.2009.10.024</doi><tpages>4</tpages></addata></record> |
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subjects | Adolescent Adult Adult and adolescent clinical studies Age of Onset Biological and medical sciences Bipolar affective disorder Bipolar disorder Bipolar Disorder - diagnosis Bipolar Disorder - epidemiology Bipolar Disorder - psychology Bipolar disorders Childlessness Children Depression Depressive Disorder, Major - diagnosis Depressive Disorder, Major - epidemiology Depressive Disorder, Major - psychology Depressive personality disorders Family Characteristics Female Health Surveys Humans Male Medical sciences Men Middle Aged Mood disorders Odds Ratio Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Reproductive Behavior - psychology Reproductive Behavior - statistics & numerical data Sex Factors United States Young Adult |
title | Early-onset major depressive disorder in men is associated with childlessness |
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