Early-onset major depressive disorder in men is associated with childlessness

Abstract Methods The self-reported number of children was compared for men and women from the National Epidemiologic Survey of Alcoholism and Related Conditions Survey (NESARC). Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disord...

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Veröffentlicht in:Journal of affective disorders 2010-07, Vol.124 (1), p.187-190
Hauptverfasser: Yates, William R, Meller, William H, Lund, Brian C, Thurber, Steve, Grambsch, Patricia L
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container_end_page 190
container_issue 1
container_start_page 187
container_title Journal of affective disorders
container_volume 124
creator Yates, William R
Meller, William H
Lund, Brian C
Thurber, Steve
Grambsch, Patricia L
description Abstract Methods The self-reported number of children was compared for men and women from the National Epidemiologic Survey of Alcoholism and Related Conditions Survey (NESARC). Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disorder. The effect of age, gender, marriage and diagnostic status on number of children was completed using multivariate analyses. Results Men with a history of major depressive disorder but not bipolar disorder reported higher rates of childlessness and lower mean number of children. This reduced number of children was related to an early age of onset of MDD. Thirty percent of men with an age of onset of MDD before 22 were childless compared to only 18.9% of men without an axis I disorder (Odds ratio = 1.82, 95% CI = 1.45–2.27). No effect of mood disorder on number of children was found in women with major depression or bipolar disorder. Discussion This study suggests that an early age of onset of major depressive disorder contributes to childlessness in men.
doi_str_mv 10.1016/j.jad.2009.10.024
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Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disorder. The effect of age, gender, marriage and diagnostic status on number of children was completed using multivariate analyses. Results Men with a history of major depressive disorder but not bipolar disorder reported higher rates of childlessness and lower mean number of children. This reduced number of children was related to an early age of onset of MDD. Thirty percent of men with an age of onset of MDD before 22 were childless compared to only 18.9% of men without an axis I disorder (Odds ratio = 1.82, 95% CI = 1.45–2.27). No effect of mood disorder on number of children was found in women with major depression or bipolar disorder. Discussion This study suggests that an early age of onset of major depressive disorder contributes to childlessness in men.</description><identifier>ISSN: 0165-0327</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/j.jad.2009.10.024</identifier><identifier>PMID: 19931182</identifier><identifier>CODEN: JADID7</identifier><language>eng</language><publisher>Oxford: Elsevier B.V</publisher><subject>Adolescent ; Adult ; Adult and adolescent clinical studies ; Age of Onset ; Biological and medical sciences ; Bipolar affective disorder ; Bipolar disorder ; Bipolar Disorder - diagnosis ; Bipolar Disorder - epidemiology ; Bipolar Disorder - psychology ; Bipolar disorders ; Childlessness ; Children ; Depression ; Depressive Disorder, Major - diagnosis ; Depressive Disorder, Major - epidemiology ; Depressive Disorder, Major - psychology ; Depressive personality disorders ; Family Characteristics ; Female ; Health Surveys ; Humans ; Male ; Medical sciences ; Men ; Middle Aged ; Mood disorders ; Odds Ratio ; Psychiatry ; Psychology. 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Subjects with a diagnosis of major depressive disorder or bipolar disorder were compared to those without an axis I disorder. The effect of age, gender, marriage and diagnostic status on number of children was completed using multivariate analyses. Results Men with a history of major depressive disorder but not bipolar disorder reported higher rates of childlessness and lower mean number of children. This reduced number of children was related to an early age of onset of MDD. Thirty percent of men with an age of onset of MDD before 22 were childless compared to only 18.9% of men without an axis I disorder (Odds ratio = 1.82, 95% CI = 1.45–2.27). No effect of mood disorder on number of children was found in women with major depression or bipolar disorder. Discussion This study suggests that an early age of onset of major depressive disorder contributes to childlessness in men.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Age of Onset</subject><subject>Biological and medical sciences</subject><subject>Bipolar affective disorder</subject><subject>Bipolar disorder</subject><subject>Bipolar Disorder - diagnosis</subject><subject>Bipolar Disorder - epidemiology</subject><subject>Bipolar Disorder - psychology</subject><subject>Bipolar disorders</subject><subject>Childlessness</subject><subject>Children</subject><subject>Depression</subject><subject>Depressive Disorder, Major - diagnosis</subject><subject>Depressive Disorder, Major - epidemiology</subject><subject>Depressive Disorder, Major - psychology</subject><subject>Depressive personality disorders</subject><subject>Family Characteristics</subject><subject>Female</subject><subject>Health Surveys</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Men</subject><subject>Middle Aged</subject><subject>Mood disorders</subject><subject>Odds Ratio</subject><subject>Psychiatry</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Reproductive Behavior - psychology</subject><subject>Reproductive Behavior - statistics &amp; numerical data</subject><subject>Sex Factors</subject><subject>United States</subject><subject>Young Adult</subject><issn>0165-0327</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqFkk2LFDEQhoMo7rj6A7xILrKnHisf3Z1GEJZl1YUVD-o5pJNqNm1_jKmeXebfm2YGBQ_uIYSE560UT4qx1wK2AkT1rt_2LmwlQJPPW5D6CduIslaFLEX9lG0yUxagZH3GXhD1AFA1NTxnZ6JplBBGbtiXa5eGQzFPhAsfXT8nHnCXkCjeIw-R5hQw8TjxESceiTui2Ue3YOAPcbnj_i4OYcj8lNdL9qxzA-Gr037Ofny8_n71ubj9-unm6vK28LpqliIYlZtWJhjpW-WVM1B2uvVOtqqpAOoGq1KU0gmhseuCgLJtOxlc0KZV2qhzdnGsu0vzrz3SYsdIHofBTTjvydZa1rI2pXicVBpkVVU6k-JI-jQTJezsLsXRpYMVYFfdtrdZt111r1dZd868OVXftyOGv4mT3wy8PQGOvBu65CYf6Q8npVFGVZC590cOs7X7iMmSjzh5DDGhX2yY43_b-PBP2g9xivnBn3hA6ud9mvJ3WGFJWrDf1rlYxwIaAG20Vr8BrTqxOA</recordid><startdate>20100701</startdate><enddate>20100701</enddate><creator>Yates, William R</creator><creator>Meller, William H</creator><creator>Lund, Brian C</creator><creator>Thurber, Steve</creator><creator>Grambsch, Patricia L</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QJ</scope></search><sort><creationdate>20100701</creationdate><title>Early-onset major depressive disorder in men is associated with childlessness</title><author>Yates, William R ; Meller, William H ; Lund, Brian C ; Thurber, Steve ; Grambsch, Patricia L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c469t-d8320038d82cb3c3a805f4bca2b3960079e65152a114effd105bbf2dad48b3483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Age of Onset</topic><topic>Biological and medical sciences</topic><topic>Bipolar affective disorder</topic><topic>Bipolar disorder</topic><topic>Bipolar Disorder - diagnosis</topic><topic>Bipolar Disorder - epidemiology</topic><topic>Bipolar Disorder - psychology</topic><topic>Bipolar disorders</topic><topic>Childlessness</topic><topic>Children</topic><topic>Depression</topic><topic>Depressive Disorder, Major - diagnosis</topic><topic>Depressive Disorder, Major - epidemiology</topic><topic>Depressive Disorder, Major - psychology</topic><topic>Depressive personality disorders</topic><topic>Family Characteristics</topic><topic>Female</topic><topic>Health Surveys</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Men</topic><topic>Middle Aged</topic><topic>Mood disorders</topic><topic>Odds Ratio</topic><topic>Psychiatry</topic><topic>Psychology. 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Psychiatry</topic><topic>Reproductive Behavior - psychology</topic><topic>Reproductive Behavior - statistics &amp; numerical data</topic><topic>Sex Factors</topic><topic>United States</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yates, William R</creatorcontrib><creatorcontrib>Meller, William H</creatorcontrib><creatorcontrib>Lund, Brian C</creatorcontrib><creatorcontrib>Thurber, Steve</creatorcontrib><creatorcontrib>Grambsch, Patricia L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Applied Social Sciences Index &amp; Abstracts (ASSIA)</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yates, William R</au><au>Meller, William H</au><au>Lund, Brian C</au><au>Thurber, Steve</au><au>Grambsch, Patricia L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early-onset major depressive disorder in men is associated with childlessness</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>2010-07-01</date><risdate>2010</risdate><volume>124</volume><issue>1</issue><spage>187</spage><epage>190</epage><pages>187-190</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><coden>JADID7</coden><abstract>Abstract Methods The self-reported number of children was compared for men and women from the National Epidemiologic Survey of Alcoholism and Related Conditions Survey (NESARC). 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subjects Adolescent
Adult
Adult and adolescent clinical studies
Age of Onset
Biological and medical sciences
Bipolar affective disorder
Bipolar disorder
Bipolar Disorder - diagnosis
Bipolar Disorder - epidemiology
Bipolar Disorder - psychology
Bipolar disorders
Childlessness
Children
Depression
Depressive Disorder, Major - diagnosis
Depressive Disorder, Major - epidemiology
Depressive Disorder, Major - psychology
Depressive personality disorders
Family Characteristics
Female
Health Surveys
Humans
Male
Medical sciences
Men
Middle Aged
Mood disorders
Odds Ratio
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Reproductive Behavior - psychology
Reproductive Behavior - statistics & numerical data
Sex Factors
United States
Young Adult
title Early-onset major depressive disorder in men is associated with childlessness
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