Structural limitations on the bifunctional intercalation of diacridines into DNA

An homologous series of diacridines containing two 9-aminoacridine chromophores linked via a simple methylene chain has been studied in order to investigate the minimum interchromophore separation required to permit bifunctional intercalation. Viscometric, sedimentation, and electric dichroism exper...

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Veröffentlicht in:	Biochemistry (Easton) 1978-11, Vol.17 (23), p.5057-5063
Hauptverfasser:	Wakelin, L. P. G, Romanos, M, Chen, T. K, Glaubiger, D, Canellakis, E. S, Waring, M. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acridines Animals Cattle Chemical Phenomena Chemistry DNA DNA, Circular Molecular Conformation Nucleic Acid Conformation Structure-Activity Relationship Thymus Gland Viscosity
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