Sensitization of clonogenic malignant cells to hyperthermia by glucose-mediated, tumor-selective pH reduction

The fraction of clonogenic cells (as assayed by colony formation in semisolid agar medium) in neurogenic TV1A tumor transplants carried subcutaneously by hyperglycemic BDIX rats (serum glucose concentration 50 mmoles/1; average intratumoral pH 6.1) was reduced by a factor of approximately 2.5 X 10(3...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 1982-01, Vol.104 (1-2), p.23-30
Hauptverfasser:	Jähde, E, Rajewsky, M F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Glucose - analysis Glucose - pharmacology Hot Temperature - therapeutic use Hydrogen-Ion Concentration Male Neoplasms, Experimental - metabolism Neoplasms, Experimental - therapy Rats Rats, Inbred Strains
Online-Zugang:	Volltext
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