Vaccine against hepatitis B--18 months prevention in a high risk setting

The development of a vaccine against hepatitis B prepared with purified and inactivated HBs Ag is described. This vaccine has been applied in patients and staff members of haemodialysis centres. Safety and efficiency of the vaccine are very satisfactory. The response of patients to immunisation was...

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Veröffentlicht in:Medical microbiology and immunology 1978-11, Vol.166 (1-4), p.109-118
Hauptverfasser: Maupas, P, Goudeau, A, Coursaget, P, Drucker, J, Bagros, P, Baudin, S, Geslin, N
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container_end_page 118
container_issue 1-4
container_start_page 109
container_title Medical microbiology and immunology
container_volume 166
creator Maupas, P
Goudeau, A
Coursaget, P
Drucker, J
Bagros, P
Baudin, S
Geslin, N
description The development of a vaccine against hepatitis B prepared with purified and inactivated HBs Ag is described. This vaccine has been applied in patients and staff members of haemodialysis centres. Safety and efficiency of the vaccine are very satisfactory. The response of patients to immunisation was significantly lower compared to the response of the staff members. None of the volunteers who had a primary response to immunisation developed signs of clinical or biological hepatitis.
doi_str_mv 10.1007/BF02121140
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source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Hepatitis B - prevention & control
Hepatitis B Antibodies - biosynthesis
Hepatitis B Surface Antigens - immunology
Humans
Immunization
Immunization, Secondary
Renal Dialysis
Vaccines, Attenuated - standards
Viral Vaccines - standards
title Vaccine against hepatitis B--18 months prevention in a high risk setting
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