Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex

Human platelet membrane glycoproteins IIb and III are two major integral membrane components that have been identified as sites mediating thrombin-induced aggregation. For purposes of our study, glycoproteins IIb and III were solubilized by extracting platelet plasma membranes with a buffer containi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 1982-09, Vol.257 (17), p.10458-10466
Hauptverfasser:	Jennings, L K, Phillips, D R
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Platelets - metabolism Calcium - pharmacology Cell Membrane - metabolism Glycoproteins - isolation & purification Humans Membrane Proteins - isolation & purification Molecular Weight Platelet Membrane Glycoproteins Protein Conformation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!