The production of COFAL test antiserum in hamsters

The production of COFAL test antiserum in hamsters

Suitable quantities of antiserum for routine COFAL testing may be readily obtained at relatively low cost by the inoculation of newborn hamsters with a chorioallantoic membrane suspension of Schmidt-Ruppin strain of avian sarcoma virus. Serum from hamsters which do not develop easily observable cuta...

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Veröffentlicht in:Journal of biological standardization 1978-07, Vol.6 (3), p.201-204
Hauptverfasser: Frerichs, G.N., Muskett, J.C.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Animals, Newborn - immunology
Antibodies, Viral - biosynthesis
Avian Leukosis Virus - analysis
Complement Fixation Tests - methods
Cricetinae
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Zusammenfassung:Suitable quantities of antiserum for routine COFAL testing may be readily obtained at relatively low cost by the inoculation of newborn hamsters with a chorioallantoic membrane suspension of Schmidt-Ruppin strain of avian sarcoma virus. Serum from hamsters which do not develop easily observable cutaneous tumours within 3 months may contain as much group specific complement-fixing antibody as serum from animals which do develop such tumours.
ISSN:0092-1157
DOI:10.1016/S0092-1157(78)80005-5