Achalasia sicca--juvenile Sjögren's syndrome with achalasia and gastric hyposecretion
Sjögren's syndrome (SS) in its classical form, which includes keratoconjunctivitis sicca, xerostomia and recurrent enlargement of the salivary glands, is associated with a connective tissue disease in at least half the patients. According to the present study of three patients with SS, achalasi...
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Veröffentlicht in: | European journal of pediatrics 1978-10, Vol.129 (3), p.175-181 |
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creator | Similä, S Kokkonen, J Kaski, M |
description | Sjögren's syndrome (SS) in its classical form, which includes keratoconjunctivitis sicca, xerostomia and recurrent enlargement of the salivary glands, is associated with a connective tissue disease in at least half the patients. According to the present study of three patients with SS, achalasia and gastric hyposecretion seem to be either further manifestations of SS, or separate phenomena associated with SS. The gastric hyposecretion involves both the hydrochloric acid and the total volume of the secretion, but the gastric mucosa has a normal appearance on microscopy. Because of the simultaneous presence of achalasia, gastric hyposecretion and reduced salivation, we have called the combination "achalasia sicca". The reduction in the secretions of the upper gastrointestinal tract might have a pathogenic association with achalasia. |
doi_str_mv | 10.1007/BF00442161 |
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According to the present study of three patients with SS, achalasia and gastric hyposecretion seem to be either further manifestations of SS, or separate phenomena associated with SS. The gastric hyposecretion involves both the hydrochloric acid and the total volume of the secretion, but the gastric mucosa has a normal appearance on microscopy. Because of the simultaneous presence of achalasia, gastric hyposecretion and reduced salivation, we have called the combination "achalasia sicca". The reduction in the secretions of the upper gastrointestinal tract might have a pathogenic association with achalasia.</description><identifier>ISSN: 0340-6199</identifier><identifier>DOI: 10.1007/BF00442161</identifier><identifier>PMID: 699923</identifier><language>eng</language><publisher>Germany</publisher><subject>Adolescent ; Child, Preschool ; Esophageal Achalasia - complications ; Female ; Gastric Juice ; Gastric Mucosa - pathology ; Humans ; Male ; Sjogren's Syndrome - complications ; Sjogren's Syndrome - pathology ; Stomach Diseases - complications ; Stomach Diseases - pathology</subject><ispartof>European journal of pediatrics, 1978-10, Vol.129 (3), p.175-181</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/699923$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Similä, S</creatorcontrib><creatorcontrib>Kokkonen, J</creatorcontrib><creatorcontrib>Kaski, M</creatorcontrib><title>Achalasia sicca--juvenile Sjögren's syndrome with achalasia and gastric hyposecretion</title><title>European journal of pediatrics</title><addtitle>Eur J Pediatr</addtitle><description>Sjögren's syndrome (SS) in its classical form, which includes keratoconjunctivitis sicca, xerostomia and recurrent enlargement of the salivary glands, is associated with a connective tissue disease in at least half the patients. According to the present study of three patients with SS, achalasia and gastric hyposecretion seem to be either further manifestations of SS, or separate phenomena associated with SS. The gastric hyposecretion involves both the hydrochloric acid and the total volume of the secretion, but the gastric mucosa has a normal appearance on microscopy. Because of the simultaneous presence of achalasia, gastric hyposecretion and reduced salivation, we have called the combination "achalasia sicca". The reduction in the secretions of the upper gastrointestinal tract might have a pathogenic association with achalasia.</description><subject>Adolescent</subject><subject>Child, Preschool</subject><subject>Esophageal Achalasia - complications</subject><subject>Female</subject><subject>Gastric Juice</subject><subject>Gastric Mucosa - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Sjogren's Syndrome - complications</subject><subject>Sjogren's Syndrome - pathology</subject><subject>Stomach Diseases - complications</subject><subject>Stomach Diseases - pathology</subject><issn>0340-6199</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kLlOAzEYhF1whUBDTeEKqoXf9h52GSICSJEoONqV7f2TONoLezdoX4wX4MVYKRHVSKNvRpoh5IrBHQPI7h8WAHHMWcqOyAREDFHKlDoj5yFsYQQUk6fkJFVKcTEhnzO70aUOTtPgrNVRtO13WLsS6dv292ftsb4NNAx14ZsK6bfrNlT_R3Rd0LUOnXeWboa2CWg9dq6pL8jxSpcBLw86JR-Lx_f5c7R8fXqZz5ZRyyHpIpGkMuGGA0iuOBMiMZkWKaJgKFcAqK0yaiXGMQpw9EEKaQzGhiWZKFBMyc2-t_XNV4-hyysXLJalrrHpQ57FXGQySUfw-gD2psIib72rtB_y_Q_iDxBfXRw</recordid><startdate>19781012</startdate><enddate>19781012</enddate><creator>Similä, S</creator><creator>Kokkonen, J</creator><creator>Kaski, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19781012</creationdate><title>Achalasia sicca--juvenile Sjögren's syndrome with achalasia and gastric hyposecretion</title><author>Similä, S ; Kokkonen, J ; Kaski, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p205t-356852b20082921335b7a36ee31e8f00eac9b9f316190e6ee0838bbe4b1573de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Adolescent</topic><topic>Child, Preschool</topic><topic>Esophageal Achalasia - complications</topic><topic>Female</topic><topic>Gastric Juice</topic><topic>Gastric Mucosa - pathology</topic><topic>Humans</topic><topic>Male</topic><topic>Sjogren's Syndrome - complications</topic><topic>Sjogren's Syndrome - pathology</topic><topic>Stomach Diseases - complications</topic><topic>Stomach Diseases - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Similä, S</creatorcontrib><creatorcontrib>Kokkonen, J</creatorcontrib><creatorcontrib>Kaski, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Similä, S</au><au>Kokkonen, J</au><au>Kaski, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Achalasia sicca--juvenile Sjögren's syndrome with achalasia and gastric hyposecretion</atitle><jtitle>European journal of pediatrics</jtitle><addtitle>Eur J Pediatr</addtitle><date>1978-10-12</date><risdate>1978</risdate><volume>129</volume><issue>3</issue><spage>175</spage><epage>181</epage><pages>175-181</pages><issn>0340-6199</issn><abstract>Sjögren's syndrome (SS) in its classical form, which includes keratoconjunctivitis sicca, xerostomia and recurrent enlargement of the salivary glands, is associated with a connective tissue disease in at least half the patients. According to the present study of three patients with SS, achalasia and gastric hyposecretion seem to be either further manifestations of SS, or separate phenomena associated with SS. The gastric hyposecretion involves both the hydrochloric acid and the total volume of the secretion, but the gastric mucosa has a normal appearance on microscopy. Because of the simultaneous presence of achalasia, gastric hyposecretion and reduced salivation, we have called the combination "achalasia sicca". The reduction in the secretions of the upper gastrointestinal tract might have a pathogenic association with achalasia.</abstract><cop>Germany</cop><pmid>699923</pmid><doi>10.1007/BF00442161</doi><tpages>7</tpages></addata></record> |
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subjects | Adolescent Child, Preschool Esophageal Achalasia - complications Female Gastric Juice Gastric Mucosa - pathology Humans Male Sjogren's Syndrome - complications Sjogren's Syndrome - pathology Stomach Diseases - complications Stomach Diseases - pathology |
title | Achalasia sicca--juvenile Sjögren's syndrome with achalasia and gastric hyposecretion |
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