Achalasia sicca--juvenile Sjögren's syndrome with achalasia and gastric hyposecretion

Sjögren's syndrome (SS) in its classical form, which includes keratoconjunctivitis sicca, xerostomia and recurrent enlargement of the salivary glands, is associated with a connective tissue disease in at least half the patients. According to the present study of three patients with SS, achalasi...

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Veröffentlicht in:European journal of pediatrics 1978-10, Vol.129 (3), p.175-181
Hauptverfasser: Similä, S, Kokkonen, J, Kaski, M
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container_title European journal of pediatrics
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creator Similä, S
Kokkonen, J
Kaski, M
description Sjögren's syndrome (SS) in its classical form, which includes keratoconjunctivitis sicca, xerostomia and recurrent enlargement of the salivary glands, is associated with a connective tissue disease in at least half the patients. According to the present study of three patients with SS, achalasia and gastric hyposecretion seem to be either further manifestations of SS, or separate phenomena associated with SS. The gastric hyposecretion involves both the hydrochloric acid and the total volume of the secretion, but the gastric mucosa has a normal appearance on microscopy. Because of the simultaneous presence of achalasia, gastric hyposecretion and reduced salivation, we have called the combination "achalasia sicca". The reduction in the secretions of the upper gastrointestinal tract might have a pathogenic association with achalasia.
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subjects Adolescent
Child, Preschool
Esophageal Achalasia - complications
Female
Gastric Juice
Gastric Mucosa - pathology
Humans
Male
Sjogren's Syndrome - complications
Sjogren's Syndrome - pathology
Stomach Diseases - complications
Stomach Diseases - pathology
title Achalasia sicca--juvenile Sjögren's syndrome with achalasia and gastric hyposecretion
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