Classification of Trimethoprim‐Resistant Dihydrofolate Reductases Mediated by R‐Plasmids Using Isoelectric Focussing

An analytical isoelectric focussing technique has been developed to distinguish between different groups of R‐plasmid‐mediated trimethoprim‐resistant dihydrofolate reductases. Those mediated by the R‐plasmids R483 and R721, which are type I dihydrofolate reductases have isoelectric point (PI) values...

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Veröffentlicht in:	European journal of biochemistry 1982-07, Vol.125 (3), p.617-622
Hauptverfasser:	BROAD, David F., SMITH, John T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatography, Ion Exchange - methods Escherichia coli Escherichia coli - enzymology Folic Acid Antagonists Isoelectric Focusing - methods R Factors Swine Temperature Tetrahydrofolate Dehydrogenase - genetics Trimethoprim - pharmacology
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