Effects of ovariectomy and hormone replacement of DRL behavior in the rat

Fifty-two female rats were sham-operated or ovariectomized. Groups of ovariectomized animals were sham-implanted or implanted with estradiol, progesterone or a combination of estrogen and progesterone. Assays were conducted to determine serum hormone concentrations. Animals were trained on a DRL-20...

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Veröffentlicht in:Physiology & behavior 1978-04, Vol.20 (4), p.477-480
Hauptverfasser: Lentz, Francis E., Pool, Gary L., Milner, Joel S.
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creator Lentz, Francis E.
Pool, Gary L.
Milner, Joel S.
description Fifty-two female rats were sham-operated or ovariectomized. Groups of ovariectomized animals were sham-implanted or implanted with estradiol, progesterone or a combination of estrogen and progesterone. Assays were conducted to determine serum hormone concentrations. Animals were trained on a DRL-20 schedule for 30 days. During DRL, ovariectomized animals showed an increased response rate relative to intact animals. However, DRL performance data indicated ovariectomized rats did not differ significantly from intact female rats or hormone replacement groups on measures of DRL efficiency or on the number of earned reinforcers.
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Animals
Castration
Conditioning, Operant - drug effects
Conditioning, Operant - physiology
DRL
Estradiol - pharmacology
Estrogen
Estrogens - physiology
Feeding Behavior - drug effects
Feeding Behavior - physiology
Female
Hormone replacement
Ovariectomy
Progesterone
Progesterone - pharmacology
Progesterone - physiology
Rats
Sex Factors
title Effects of ovariectomy and hormone replacement of DRL behavior in the rat
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