Enteritis due to feline infectious peritonitis virus [Japan]

Four clinically, pathologically and serologically diagnosed cases of fatal feline infectious peritonitis (FIP) as well as 14 experimentally infected cases were examined for gut lesions and local presence of viral antigen and particles by immunofluorescence or electronmicroscopy, respectively. Two of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Japanese journal of veterinary science 1982/02/25, Vol.44(1), pp.97-103,106
Hauptverfasser: Hayashi, T, Watabe, Y, Nakayama, H, Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 103,106
container_issue 1
container_start_page 97
container_title Japanese journal of veterinary science
container_volume 44
creator Hayashi, T
Watabe, Y
Nakayama, H
Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)
description Four clinically, pathologically and serologically diagnosed cases of fatal feline infectious peritonitis (FIP) as well as 14 experimentally infected cases were examined for gut lesions and local presence of viral antigen and particles by immunofluorescence or electronmicroscopy, respectively. Two of 4 naturally occurring cases and 12 of 14 orally infected cases had diarrhea. In most of these cases the small and large intestines showed edematous thickening of either anemic or hyperemic mucosa with watery or mucous content. Histopathologically the enteric lesions in 3 natural and 12 experimental cases were rather superficial and characterized by degeneration, desquamation and hyperplasia of epithelial cells and edematous tunica propria with some infiltration of neutrophils and mononuclear cells. Fusion of epithelial cells was frequently encountered. In the remaining 1 natural and 2 experimental fatal cases, however, the deep mucosa of the small and large intestines was also severely affected with remarkable cell infiltration. By immunofluorescence virus-specific antigen was detected in the cytoplasm of intestinal epithelial cells of natural as well as experimental cases. Electronmicroscopy revealed coronavirus particles within the same cells as well as in feces. The findings suggest that fecal excretion of the virus from intestinal lesion may be of importance for transmission of FIP.
doi_str_mv 10.1292/jvms1939.44.97
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_74147155</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>74147155</sourcerecordid><originalsourceid>FETCH-LOGICAL-c466t-7b3d2523a02d3d54cc3cd9483988bf334e3f1c07e3b253772d8b17dc3980b3613</originalsourceid><addsrcrecordid>eNpVkM1LwzAYh4Moc06vHgShJ2-t-WwS8CJjfjHQg55EQpqmM6NfJu3A_97OzoGXvJDneX-8_AA4RzBBWOLr9aYKSBKZUJpIfgCmSAgUI0rxIZhCiFHMsGTH4CSENYRUCsgnYJJiwSBLp-BmUXfWu86FKO9t1DVRYUtX28jVhTWda_oQtVuhqX-ljfPDz_uTbnX9cQqOCl0Ge7abM_B2t3idP8TL5_vH-e0yNjRNu5hnJMcMEw1xTnJGjSEml1QQKURWEEItKZCB3JIMM8I5zkWGeG4GDjOSIjIDV2Nu65uv3oZOVS4YW5a6tsOBilNEOWJsEJNRNL4JwdtCtd5V2n8rBNW2LvVXl6JUST4sXO6S-6yy-V7f9TPw-cjXodMru-fad86U9l8cGh_J99R8aq9sPaRcjCmFbpReeRfU04vAkG1v_gEIgYYS</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>74147155</pqid></control><display><type>article</type><title>Enteritis due to feline infectious peritonitis virus [Japan]</title><source>J-STAGE Free</source><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>AgriKnowledge(アグリナレッジ)AGROLib</source><creator>Hayashi, T ; Watabe, Y ; Nakayama, H ; Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)</creator><creatorcontrib>Hayashi, T ; Watabe, Y ; Nakayama, H ; Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)</creatorcontrib><description>Four clinically, pathologically and serologically diagnosed cases of fatal feline infectious peritonitis (FIP) as well as 14 experimentally infected cases were examined for gut lesions and local presence of viral antigen and particles by immunofluorescence or electronmicroscopy, respectively. Two of 4 naturally occurring cases and 12 of 14 orally infected cases had diarrhea. In most of these cases the small and large intestines showed edematous thickening of either anemic or hyperemic mucosa with watery or mucous content. Histopathologically the enteric lesions in 3 natural and 12 experimental cases were rather superficial and characterized by degeneration, desquamation and hyperplasia of epithelial cells and edematous tunica propria with some infiltration of neutrophils and mononuclear cells. Fusion of epithelial cells was frequently encountered. In the remaining 1 natural and 2 experimental fatal cases, however, the deep mucosa of the small and large intestines was also severely affected with remarkable cell infiltration. By immunofluorescence virus-specific antigen was detected in the cytoplasm of intestinal epithelial cells of natural as well as experimental cases. Electronmicroscopy revealed coronavirus particles within the same cells as well as in feces. The findings suggest that fecal excretion of the virus from intestinal lesion may be of importance for transmission of FIP.</description><identifier>ISSN: 0021-5295</identifier><identifier>EISSN: 1881-1442</identifier><identifier>DOI: 10.1292/jvms1939.44.97</identifier><identifier>PMID: 6285056</identifier><language>eng</language><publisher>Japan: JAPANESE SOCIETY OF VETERINARY SCIENCE</publisher><subject>ANIMALS ; ASIA ; BEHAVIOUR ; CARNIVORES ; Cat Diseases - etiology ; CATS ; CORONAVIRIDAE ; Coronaviridae Infections - complications ; Coronaviridae Infections - veterinary ; DIGESTIVE SYSTEM DISEASES ; DISEASES ; DOMESTIC ANIMALS ; Enteritis - etiology ; Enteritis - veterinary ; FEEDING HABITS ; FELIDAE ; FUR-BEARING ANIMALS ; INJURIOUS FACTORS ; JAPAN ; LABORATORY ANIMALS ; MAMMALS ; ORGANIC DISEASES ; PET ANIMALS ; VERTEBRATES ; VIRUSES</subject><ispartof>The Japanese Journal of Veterinary Science, 1982/02/25, Vol.44(1), pp.97-103,106</ispartof><rights>The Japanese Society of Veterinary Science</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c466t-7b3d2523a02d3d54cc3cd9483988bf334e3f1c07e3b253772d8b17dc3980b3613</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6285056$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hayashi, T</creatorcontrib><creatorcontrib>Watabe, Y</creatorcontrib><creatorcontrib>Nakayama, H</creatorcontrib><creatorcontrib>Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)</creatorcontrib><title>Enteritis due to feline infectious peritonitis virus [Japan]</title><title>Japanese journal of veterinary science</title><addtitle>The Japanese Journal of Veterinary Science</addtitle><description>Four clinically, pathologically and serologically diagnosed cases of fatal feline infectious peritonitis (FIP) as well as 14 experimentally infected cases were examined for gut lesions and local presence of viral antigen and particles by immunofluorescence or electronmicroscopy, respectively. Two of 4 naturally occurring cases and 12 of 14 orally infected cases had diarrhea. In most of these cases the small and large intestines showed edematous thickening of either anemic or hyperemic mucosa with watery or mucous content. Histopathologically the enteric lesions in 3 natural and 12 experimental cases were rather superficial and characterized by degeneration, desquamation and hyperplasia of epithelial cells and edematous tunica propria with some infiltration of neutrophils and mononuclear cells. Fusion of epithelial cells was frequently encountered. In the remaining 1 natural and 2 experimental fatal cases, however, the deep mucosa of the small and large intestines was also severely affected with remarkable cell infiltration. By immunofluorescence virus-specific antigen was detected in the cytoplasm of intestinal epithelial cells of natural as well as experimental cases. Electronmicroscopy revealed coronavirus particles within the same cells as well as in feces. The findings suggest that fecal excretion of the virus from intestinal lesion may be of importance for transmission of FIP.</description><subject>ANIMALS</subject><subject>ASIA</subject><subject>BEHAVIOUR</subject><subject>CARNIVORES</subject><subject>Cat Diseases - etiology</subject><subject>CATS</subject><subject>CORONAVIRIDAE</subject><subject>Coronaviridae Infections - complications</subject><subject>Coronaviridae Infections - veterinary</subject><subject>DIGESTIVE SYSTEM DISEASES</subject><subject>DISEASES</subject><subject>DOMESTIC ANIMALS</subject><subject>Enteritis - etiology</subject><subject>Enteritis - veterinary</subject><subject>FEEDING HABITS</subject><subject>FELIDAE</subject><subject>FUR-BEARING ANIMALS</subject><subject>INJURIOUS FACTORS</subject><subject>JAPAN</subject><subject>LABORATORY ANIMALS</subject><subject>MAMMALS</subject><subject>ORGANIC DISEASES</subject><subject>PET ANIMALS</subject><subject>VERTEBRATES</subject><subject>VIRUSES</subject><issn>0021-5295</issn><issn>1881-1442</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM1LwzAYh4Moc06vHgShJ2-t-WwS8CJjfjHQg55EQpqmM6NfJu3A_97OzoGXvJDneX-8_AA4RzBBWOLr9aYKSBKZUJpIfgCmSAgUI0rxIZhCiFHMsGTH4CSENYRUCsgnYJJiwSBLp-BmUXfWu86FKO9t1DVRYUtX28jVhTWda_oQtVuhqX-ljfPDz_uTbnX9cQqOCl0Ge7abM_B2t3idP8TL5_vH-e0yNjRNu5hnJMcMEw1xTnJGjSEml1QQKURWEEItKZCB3JIMM8I5zkWGeG4GDjOSIjIDV2Nu65uv3oZOVS4YW5a6tsOBilNEOWJsEJNRNL4JwdtCtd5V2n8rBNW2LvVXl6JUST4sXO6S-6yy-V7f9TPw-cjXodMru-fad86U9l8cGh_J99R8aq9sPaRcjCmFbpReeRfU04vAkG1v_gEIgYYS</recordid><startdate>19820101</startdate><enddate>19820101</enddate><creator>Hayashi, T</creator><creator>Watabe, Y</creator><creator>Nakayama, H</creator><creator>Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)</creator><general>JAPANESE SOCIETY OF VETERINARY SCIENCE</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19820101</creationdate><title>Enteritis due to feline infectious peritonitis virus [Japan]</title><author>Hayashi, T ; Watabe, Y ; Nakayama, H ; Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c466t-7b3d2523a02d3d54cc3cd9483988bf334e3f1c07e3b253772d8b17dc3980b3613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>ANIMALS</topic><topic>ASIA</topic><topic>BEHAVIOUR</topic><topic>CARNIVORES</topic><topic>Cat Diseases - etiology</topic><topic>CATS</topic><topic>CORONAVIRIDAE</topic><topic>Coronaviridae Infections - complications</topic><topic>Coronaviridae Infections - veterinary</topic><topic>DIGESTIVE SYSTEM DISEASES</topic><topic>DISEASES</topic><topic>DOMESTIC ANIMALS</topic><topic>Enteritis - etiology</topic><topic>Enteritis - veterinary</topic><topic>FEEDING HABITS</topic><topic>FELIDAE</topic><topic>FUR-BEARING ANIMALS</topic><topic>INJURIOUS FACTORS</topic><topic>JAPAN</topic><topic>LABORATORY ANIMALS</topic><topic>MAMMALS</topic><topic>ORGANIC DISEASES</topic><topic>PET ANIMALS</topic><topic>VERTEBRATES</topic><topic>VIRUSES</topic><toplevel>online_resources</toplevel><creatorcontrib>Hayashi, T</creatorcontrib><creatorcontrib>Watabe, Y</creatorcontrib><creatorcontrib>Nakayama, H</creatorcontrib><creatorcontrib>Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Japanese journal of veterinary science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hayashi, T</au><au>Watabe, Y</au><au>Nakayama, H</au><au>Fujiwara, K. (Tokyo Univ. (Japan). Faculty of Agriculture)</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enteritis due to feline infectious peritonitis virus [Japan]</atitle><jtitle>Japanese journal of veterinary science</jtitle><addtitle>The Japanese Journal of Veterinary Science</addtitle><date>1982-01-01</date><risdate>1982</risdate><volume>44</volume><issue>1</issue><spage>97</spage><epage>103,106</epage><pages>97-103,106</pages><issn>0021-5295</issn><eissn>1881-1442</eissn><abstract>Four clinically, pathologically and serologically diagnosed cases of fatal feline infectious peritonitis (FIP) as well as 14 experimentally infected cases were examined for gut lesions and local presence of viral antigen and particles by immunofluorescence or electronmicroscopy, respectively. Two of 4 naturally occurring cases and 12 of 14 orally infected cases had diarrhea. In most of these cases the small and large intestines showed edematous thickening of either anemic or hyperemic mucosa with watery or mucous content. Histopathologically the enteric lesions in 3 natural and 12 experimental cases were rather superficial and characterized by degeneration, desquamation and hyperplasia of epithelial cells and edematous tunica propria with some infiltration of neutrophils and mononuclear cells. Fusion of epithelial cells was frequently encountered. In the remaining 1 natural and 2 experimental fatal cases, however, the deep mucosa of the small and large intestines was also severely affected with remarkable cell infiltration. By immunofluorescence virus-specific antigen was detected in the cytoplasm of intestinal epithelial cells of natural as well as experimental cases. Electronmicroscopy revealed coronavirus particles within the same cells as well as in feces. The findings suggest that fecal excretion of the virus from intestinal lesion may be of importance for transmission of FIP.</abstract><cop>Japan</cop><pub>JAPANESE SOCIETY OF VETERINARY SCIENCE</pub><pmid>6285056</pmid><doi>10.1292/jvms1939.44.97</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0021-5295
ispartof The Japanese Journal of Veterinary Science, 1982/02/25, Vol.44(1), pp.97-103,106
issn 0021-5295
1881-1442
language eng
recordid cdi_proquest_miscellaneous_74147155
source J-STAGE Free; MEDLINE; EZB-FREE-00999 freely available EZB journals; AgriKnowledge(アグリナレッジ)AGROLib
subjects ANIMALS
ASIA
BEHAVIOUR
CARNIVORES
Cat Diseases - etiology
CATS
CORONAVIRIDAE
Coronaviridae Infections - complications
Coronaviridae Infections - veterinary
DIGESTIVE SYSTEM DISEASES
DISEASES
DOMESTIC ANIMALS
Enteritis - etiology
Enteritis - veterinary
FEEDING HABITS
FELIDAE
FUR-BEARING ANIMALS
INJURIOUS FACTORS
JAPAN
LABORATORY ANIMALS
MAMMALS
ORGANIC DISEASES
PET ANIMALS
VERTEBRATES
VIRUSES
title Enteritis due to feline infectious peritonitis virus [Japan]
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T21%3A00%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Enteritis%20due%20to%20feline%20infectious%20peritonitis%20virus%20%5BJapan%5D&rft.jtitle=Japanese%20journal%20of%20veterinary%20science&rft.au=Hayashi,%20T&rft.date=1982-01-01&rft.volume=44&rft.issue=1&rft.spage=97&rft.epage=103,106&rft.pages=97-103,106&rft.issn=0021-5295&rft.eissn=1881-1442&rft_id=info:doi/10.1292/jvms1939.44.97&rft_dat=%3Cproquest_cross%3E74147155%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=74147155&rft_id=info:pmid/6285056&rfr_iscdi=true