Cortical depth changes in enriched and isolated mice

The occipital cortical depth was determined in laboratory mice at both 14 and 20 days of age and after various periods of postweaning exposure to enrichment or isolation. The depth was found to be maximal at 20 days of age. It declined thereafter, irrespective of environment, but the isolate cortica...

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Veröffentlicht in:Developmental psychobiology 1982-05, Vol.15 (3), p.187-195
Hauptverfasser: Cummins, R. A., Livesey, P. J., Bell, J. A.
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Livesey, P. J.
Bell, J. A.
description The occipital cortical depth was determined in laboratory mice at both 14 and 20 days of age and after various periods of postweaning exposure to enrichment or isolation. The depth was found to be maximal at 20 days of age. It declined thereafter, irrespective of environment, but the isolate cortical depth decreased faster than the enriched. The postweaning depth of the occipital cortex appears to be determined by an inevitable age‐related decrease whose rate of decline may be attenuated by sensory stimulation. The postweaning cortical depth may reflect the extent of cortical neuronal development and associated metabolic activity.
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source Wiley-Blackwell Journals; MEDLINE
subjects Age Factors
Animals
Diencephalon - anatomy & histology
Mice
Occipital Lobe - anatomy & histology
Organ Size
Social Environment
Social Isolation
title Cortical depth changes in enriched and isolated mice
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