Sensitivity of cat papillary muscles to verapamil and nifedipine: enhanced effect in acidosis

The effects of acidosis on the myocardial sensitivity to verapamil and nifedipine were examined by measuring the changes in tension in cat papillary muscles perfused in oxygenated physiological saline. Calcium concentration was altered over a range of 2 to 12 mmol·litre−1 and pH adjusted to 7.4, 6.8...

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Veröffentlicht in:	Cardiovascular research 1982-04, Vol.16 (4), p.173-177
Hauptverfasser:	BRISCOE, MARTYN G, SMITH, HOWARD J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Calcium - metabolism Cardiovascular system Cats Hydrogen-Ion Concentration Medical sciences Miscellaneous Myocardial Contraction - drug effects Myocardium - metabolism Nifedipine - pharmacology Papillary Muscles - drug effects Pharmacology. Drug treatments Pyridines - pharmacology Verapamil - pharmacology
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