Naloxone does not affect pain sensitivity, mood or cognition in patients with high levels of beta-endorphin in plasma
Patients with either Cushing's or Nelson's syndrome, both of which are associated with markedly increased levels of beta-endorphin immunoreactivity in plasma, were given tests of pain sensitivity, mood, and cognition following administration of 10 mg naloxone and saline on separate days. N...
Gespeichert in:
| Veröffentlicht in: | Life sciences (1973) 1982-05, Vol.30 (21), p.1827-1833 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1833 |
|---|---|
| container_issue | 21 |
| container_start_page | 1827 |
| container_title | Life sciences (1973) |
| container_volume | 30 |
| creator | Mohs, Richard C. Davis, Bonnie M. Rosenberg, Gordon S. Davis, Kenneth L. Krieger, Dorothy T. |
| description | Patients with either Cushing's or Nelson's syndrome, both of which are associated with markedly increased levels of beta-endorphin immunoreactivity in plasma, were given tests of pain sensitivity, mood, and cognition following administration of 10 mg naloxone and saline on separate days. No differences were found between naloxone and saline administrations on any of these psychological measures. These results suggest that immunoreactive beta- endorphin in plasma does not exert opiate effects. |
| doi_str_mv | 10.1016/0024-3205(82)90320-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_74137559</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0024320582903204</els_id><sourcerecordid>74137559</sourcerecordid><originalsourceid>FETCH-LOGICAL-c357t-570cfb1ec648c9c8ecbef0cd584243f0ede6f7a883c16b76c0d4fca6ba59c333</originalsourceid><addsrcrecordid>eNp9kFFLHDEQx4NU7Kn9BhbyVCq4Ndkku9kXoUhbBbEvvodsMvFSdpNtkjvrt2-ud_jYpxnm_5sZ-CF0QckXSmh3TUjLG9YS8Vm2lwOpXcOP0IrKfmhIx-g7tHpD3qPTnH8RQoTo2Qk66VopKG1XaPOop_gnBsA2QsYhFqydA1Pwon3AGUL2xW99eb3Cc4wWx4RNfA51GAOuxKKLh1AyfvFljdf-eY0n2MKUcXR4hKIbCDamZe33-KTzrM_RsdNThg-Heoaevn97ur1rHn7-uL_9-tAYJvrSiJ4YN1IwHZdmMBLMCI4YKyRvOXMELHSu11IyQ7ux7wyx3BndjVoMhjF2hj7tzy4p_t5ALmr22cA06QBxk1XPKeuFGCrI96BJMecETi3Jzzq9KkrUTrbamVQ7k0q26p9sxevax8P9zTiDfVs62K35zT6vOmDrIalsqiwD1qeqWNno___gL9eZkIQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>74137559</pqid></control><display><type>article</type><title>Naloxone does not affect pain sensitivity, mood or cognition in patients with high levels of beta-endorphin in plasma</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Mohs, Richard C. ; Davis, Bonnie M. ; Rosenberg, Gordon S. ; Davis, Kenneth L. ; Krieger, Dorothy T.</creator><creatorcontrib>Mohs, Richard C. ; Davis, Bonnie M. ; Rosenberg, Gordon S. ; Davis, Kenneth L. ; Krieger, Dorothy T.</creatorcontrib><description>Patients with either Cushing's or Nelson's syndrome, both of which are associated with markedly increased levels of beta-endorphin immunoreactivity in plasma, were given tests of pain sensitivity, mood, and cognition following administration of 10 mg naloxone and saline on separate days. No differences were found between naloxone and saline administrations on any of these psychological measures. These results suggest that immunoreactive beta- endorphin in plasma does not exert opiate effects.</description><identifier>ISSN: 0024-3205</identifier><identifier>EISSN: 1879-0631</identifier><identifier>DOI: 10.1016/0024-3205(82)90320-4</identifier><identifier>PMID: 6285112</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adult ; beta-Endorphin ; Cognition - drug effects ; Cushing Syndrome - blood ; Cushing Syndrome - psychology ; Emotions - drug effects ; Endorphins - blood ; Humans ; Middle Aged ; Naloxone - pharmacology ; Nelson Syndrome - blood ; Nelson Syndrome - psychology ; Nociceptors - drug effects</subject><ispartof>Life sciences (1973), 1982-05, Vol.30 (21), p.1827-1833</ispartof><rights>1982</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-570cfb1ec648c9c8ecbef0cd584243f0ede6f7a883c16b76c0d4fca6ba59c333</citedby><cites>FETCH-LOGICAL-c357t-570cfb1ec648c9c8ecbef0cd584243f0ede6f7a883c16b76c0d4fca6ba59c333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0024-3205(82)90320-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6285112$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mohs, Richard C.</creatorcontrib><creatorcontrib>Davis, Bonnie M.</creatorcontrib><creatorcontrib>Rosenberg, Gordon S.</creatorcontrib><creatorcontrib>Davis, Kenneth L.</creatorcontrib><creatorcontrib>Krieger, Dorothy T.</creatorcontrib><title>Naloxone does not affect pain sensitivity, mood or cognition in patients with high levels of beta-endorphin in plasma</title><title>Life sciences (1973)</title><addtitle>Life Sci</addtitle><description>Patients with either Cushing's or Nelson's syndrome, both of which are associated with markedly increased levels of beta-endorphin immunoreactivity in plasma, were given tests of pain sensitivity, mood, and cognition following administration of 10 mg naloxone and saline on separate days. No differences were found between naloxone and saline administrations on any of these psychological measures. These results suggest that immunoreactive beta- endorphin in plasma does not exert opiate effects.</description><subject>Adult</subject><subject>beta-Endorphin</subject><subject>Cognition - drug effects</subject><subject>Cushing Syndrome - blood</subject><subject>Cushing Syndrome - psychology</subject><subject>Emotions - drug effects</subject><subject>Endorphins - blood</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Naloxone - pharmacology</subject><subject>Nelson Syndrome - blood</subject><subject>Nelson Syndrome - psychology</subject><subject>Nociceptors - drug effects</subject><issn>0024-3205</issn><issn>1879-0631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kFFLHDEQx4NU7Kn9BhbyVCq4Ndkku9kXoUhbBbEvvodsMvFSdpNtkjvrt2-ud_jYpxnm_5sZ-CF0QckXSmh3TUjLG9YS8Vm2lwOpXcOP0IrKfmhIx-g7tHpD3qPTnH8RQoTo2Qk66VopKG1XaPOop_gnBsA2QsYhFqydA1Pwon3AGUL2xW99eb3Cc4wWx4RNfA51GAOuxKKLh1AyfvFljdf-eY0n2MKUcXR4hKIbCDamZe33-KTzrM_RsdNThg-Heoaevn97ur1rHn7-uL_9-tAYJvrSiJ4YN1IwHZdmMBLMCI4YKyRvOXMELHSu11IyQ7ux7wyx3BndjVoMhjF2hj7tzy4p_t5ALmr22cA06QBxk1XPKeuFGCrI96BJMecETi3Jzzq9KkrUTrbamVQ7k0q26p9sxevax8P9zTiDfVs62K35zT6vOmDrIalsqiwD1qeqWNno___gL9eZkIQ</recordid><startdate>19820524</startdate><enddate>19820524</enddate><creator>Mohs, Richard C.</creator><creator>Davis, Bonnie M.</creator><creator>Rosenberg, Gordon S.</creator><creator>Davis, Kenneth L.</creator><creator>Krieger, Dorothy T.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19820524</creationdate><title>Naloxone does not affect pain sensitivity, mood or cognition in patients with high levels of beta-endorphin in plasma</title><author>Mohs, Richard C. ; Davis, Bonnie M. ; Rosenberg, Gordon S. ; Davis, Kenneth L. ; Krieger, Dorothy T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-570cfb1ec648c9c8ecbef0cd584243f0ede6f7a883c16b76c0d4fca6ba59c333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Adult</topic><topic>beta-Endorphin</topic><topic>Cognition - drug effects</topic><topic>Cushing Syndrome - blood</topic><topic>Cushing Syndrome - psychology</topic><topic>Emotions - drug effects</topic><topic>Endorphins - blood</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Naloxone - pharmacology</topic><topic>Nelson Syndrome - blood</topic><topic>Nelson Syndrome - psychology</topic><topic>Nociceptors - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mohs, Richard C.</creatorcontrib><creatorcontrib>Davis, Bonnie M.</creatorcontrib><creatorcontrib>Rosenberg, Gordon S.</creatorcontrib><creatorcontrib>Davis, Kenneth L.</creatorcontrib><creatorcontrib>Krieger, Dorothy T.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Life sciences (1973)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mohs, Richard C.</au><au>Davis, Bonnie M.</au><au>Rosenberg, Gordon S.</au><au>Davis, Kenneth L.</au><au>Krieger, Dorothy T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Naloxone does not affect pain sensitivity, mood or cognition in patients with high levels of beta-endorphin in plasma</atitle><jtitle>Life sciences (1973)</jtitle><addtitle>Life Sci</addtitle><date>1982-05-24</date><risdate>1982</risdate><volume>30</volume><issue>21</issue><spage>1827</spage><epage>1833</epage><pages>1827-1833</pages><issn>0024-3205</issn><eissn>1879-0631</eissn><abstract>Patients with either Cushing's or Nelson's syndrome, both of which are associated with markedly increased levels of beta-endorphin immunoreactivity in plasma, were given tests of pain sensitivity, mood, and cognition following administration of 10 mg naloxone and saline on separate days. No differences were found between naloxone and saline administrations on any of these psychological measures. These results suggest that immunoreactive beta- endorphin in plasma does not exert opiate effects.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>6285112</pmid><doi>10.1016/0024-3205(82)90320-4</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0024-3205 |
| ispartof | Life sciences (1973), 1982-05, Vol.30 (21), p.1827-1833 |
| issn | 0024-3205 1879-0631 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74137559 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult beta-Endorphin Cognition - drug effects Cushing Syndrome - blood Cushing Syndrome - psychology Emotions - drug effects Endorphins - blood Humans Middle Aged Naloxone - pharmacology Nelson Syndrome - blood Nelson Syndrome - psychology Nociceptors - drug effects |
| title | Naloxone does not affect pain sensitivity, mood or cognition in patients with high levels of beta-endorphin in plasma |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T04%3A47%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Naloxone%20does%20not%20affect%20pain%20sensitivity,%20mood%20or%20cognition%20in%20patients%20with%20high%20levels%20of%20beta-endorphin%20in%20plasma&rft.jtitle=Life%20sciences%20(1973)&rft.au=Mohs,%20Richard%20C.&rft.date=1982-05-24&rft.volume=30&rft.issue=21&rft.spage=1827&rft.epage=1833&rft.pages=1827-1833&rft.issn=0024-3205&rft.eissn=1879-0631&rft_id=info:doi/10.1016/0024-3205(82)90320-4&rft_dat=%3Cproquest_cross%3E74137559%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=74137559&rft_id=info:pmid/6285112&rft_els_id=0024320582903204&rfr_iscdi=true |