Cerebrospinal fluid vasopressin and oxytocin: Evidence for an osmotic response
A push-pull perfusion technique was used to sample third ventricular cerebrospinal fluid (CSF) in the conscious rat. Ventricular perfusate contained significant quantities of vasopressin and oxytocin, 13.1 and 4.5 pg/ml, respectively. Vasopressin and oxytocin levels were stable over a 3 h perfusion...
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| Veröffentlicht in: | Neuroscience letters 1982-04, Vol.29 (3), p.275-279 |
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| container_title | Neuroscience letters |
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| creator | Barnard, Ralph R. Morris, Mariana |
| description | A push-pull perfusion technique was used to sample third ventricular cerebrospinal fluid (CSF) in the conscious rat. Ventricular perfusate contained significant quantities of vasopressin and oxytocin, 13.1 and 4.5 pg/ml, respectively. Vasopressin and oxytocin levels were stable over a 3 h perfusion period. High sodium artificial CSF elicited a 4–5-fold stimulation of perfusate concentrations of both peptides. These findings suggest that the CSF represents a dynamic compartment in terms of neuroendocrine function. |
| doi_str_mv | 10.1016/0304-3940(82)90329-9 |
| format | Article |
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These findings suggest that the CSF represents a dynamic compartment in terms of neuroendocrine function.</description><identifier>ISSN: 0304-3940</identifier><identifier>EISSN: 1872-7972</identifier><identifier>DOI: 10.1016/0304-3940(82)90329-9</identifier><identifier>PMID: 7099490</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Animals ; Cerebral Ventricles - physiology ; cerebrospinal fluid ; Male ; Osmolar Concentration ; oxytocin ; Oxytocin - cerebrospinal fluid ; Perfusion ; push-pull perfusion ; Rats ; Sodium Chloride - pharmacology ; vasopressin ; Vasopressins - cerebrospinal fluid</subject><ispartof>Neuroscience letters, 1982-04, Vol.29 (3), p.275-279</ispartof><rights>1982</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-1f2af52cc00d32aa370be875e4e11f6189ba379ae8691c106a4486b3c0f89d7b3</citedby><cites>FETCH-LOGICAL-c357t-1f2af52cc00d32aa370be875e4e11f6189ba379ae8691c106a4486b3c0f89d7b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0304-3940(82)90329-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27926,27927,45997</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7099490$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barnard, Ralph R.</creatorcontrib><creatorcontrib>Morris, Mariana</creatorcontrib><title>Cerebrospinal fluid vasopressin and oxytocin: Evidence for an osmotic response</title><title>Neuroscience letters</title><addtitle>Neurosci Lett</addtitle><description>A push-pull perfusion technique was used to sample third ventricular cerebrospinal fluid (CSF) in the conscious rat. Ventricular perfusate contained significant quantities of vasopressin and oxytocin, 13.1 and 4.5 pg/ml, respectively. Vasopressin and oxytocin levels were stable over a 3 h perfusion period. High sodium artificial CSF elicited a 4–5-fold stimulation of perfusate concentrations of both peptides. These findings suggest that the CSF represents a dynamic compartment in terms of neuroendocrine function.</description><subject>Animals</subject><subject>Cerebral Ventricles - physiology</subject><subject>cerebrospinal fluid</subject><subject>Male</subject><subject>Osmolar Concentration</subject><subject>oxytocin</subject><subject>Oxytocin - cerebrospinal fluid</subject><subject>Perfusion</subject><subject>push-pull perfusion</subject><subject>Rats</subject><subject>Sodium Chloride - pharmacology</subject><subject>vasopressin</subject><subject>Vasopressins - cerebrospinal fluid</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1LxDAQxYMo67r6Hyj0JHqoTj7aJB4EWdYPEL3oOaTpFCLdpibdRf97u-7i0dPAvPdmeD9CTilcUaDlNXAQOdcCLhS71MCZzvUemVIlWS61ZPtk-mc5JEcpfQBAQQsxIRMJWgsNU_Iyx4hVDKn3nW2zpl35OlvbFPqIKfkus12dha_vITjf3WSLta-xc5g1IY5SFtIyDN5lo7kPXcJjctDYNuHJbs7I-_3ibf6YP78-PM3vnnPHCznktGG2KZhzADVn1nIJFSpZoEBKm5IqXY07bVGVmjoKpRVClRV30Chdy4rPyPn2bh_D5wrTYJY-OWxb22FYJSMF5cAVG41ia3RjxxSxMX30Sxu_DQWzwWg2jMyGkVHM_GI0eoyd7e6vqiXWf6Edt1G_3eo4llx7jCY5vwFT-4huMHXw_z_4AbkwgeA</recordid><startdate>19820426</startdate><enddate>19820426</enddate><creator>Barnard, Ralph R.</creator><creator>Morris, Mariana</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19820426</creationdate><title>Cerebrospinal fluid vasopressin and oxytocin: Evidence for an osmotic response</title><author>Barnard, Ralph R. ; Morris, Mariana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-1f2af52cc00d32aa370be875e4e11f6189ba379ae8691c106a4486b3c0f89d7b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1982</creationdate><topic>Animals</topic><topic>Cerebral Ventricles - physiology</topic><topic>cerebrospinal fluid</topic><topic>Male</topic><topic>Osmolar Concentration</topic><topic>oxytocin</topic><topic>Oxytocin - cerebrospinal fluid</topic><topic>Perfusion</topic><topic>push-pull perfusion</topic><topic>Rats</topic><topic>Sodium Chloride - pharmacology</topic><topic>vasopressin</topic><topic>Vasopressins - cerebrospinal fluid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barnard, Ralph R.</creatorcontrib><creatorcontrib>Morris, Mariana</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barnard, Ralph R.</au><au>Morris, Mariana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cerebrospinal fluid vasopressin and oxytocin: Evidence for an osmotic response</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>1982-04-26</date><risdate>1982</risdate><volume>29</volume><issue>3</issue><spage>275</spage><epage>279</epage><pages>275-279</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><abstract>A push-pull perfusion technique was used to sample third ventricular cerebrospinal fluid (CSF) in the conscious rat. Ventricular perfusate contained significant quantities of vasopressin and oxytocin, 13.1 and 4.5 pg/ml, respectively. Vasopressin and oxytocin levels were stable over a 3 h perfusion period. High sodium artificial CSF elicited a 4–5-fold stimulation of perfusate concentrations of both peptides. These findings suggest that the CSF represents a dynamic compartment in terms of neuroendocrine function.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>7099490</pmid><doi>10.1016/0304-3940(82)90329-9</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0304-3940 |
| ispartof | Neuroscience letters, 1982-04, Vol.29 (3), p.275-279 |
| issn | 0304-3940 1872-7972 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74130382 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Animals Cerebral Ventricles - physiology cerebrospinal fluid Male Osmolar Concentration oxytocin Oxytocin - cerebrospinal fluid Perfusion push-pull perfusion Rats Sodium Chloride - pharmacology vasopressin Vasopressins - cerebrospinal fluid |
| title | Cerebrospinal fluid vasopressin and oxytocin: Evidence for an osmotic response |
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