Cleavage of IgG by Elastase-Like Protease (ELP) of Human Polymorphonuclear Leukocytes (PMN): Isolation and Characterization of Fab and Fc Fragments and Low-Molecular-Weight Peptides Stimulation of Granulocyte Function by ELP-Derived Fab and Fc Fragments

The elastase-like protease (ELP) from human polymorphonuclear granulocytes (PNM) is able to split human IgG into Fab and Fc-like fragments and smaller peptides. These fragments are similar but not identical to those produced by papain. They differ in their electrophoretical mobility as well as in th...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Immunobiology (1979) 1982-05, Vol.161 (5), p.507-523
Hauptverfasser:	Kolb, G., Köppler, H., Gramse, Margarethe, Havemann, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Humans Immunoglobulin Fab Fragments - isolation & purification Immunoglobulin Fc Fragments - isolation & purification Immunoglobulin G - metabolism Neutrophils - enzymology Neutrophils - physiology Nitroblue Tetrazolium - metabolism Pancreatic Elastase Papain Peptide Fragments - isolation & purification Peptide Hydrolases - blood Phagocytosis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!