Undifferentiated (embryonal) sarcoma of the liver. Report of 31 cases
Thirty‐one cases of undifferentiated (embryonal) sarcoma of the liver are presented. The tumor is found predominantly in the pediatric age group, the majority of patients (51.6%) being between 6 and 10 years of age. An abdominal mass and pain are the usual presenting symptoms. Radiographic examinati...
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| Veröffentlicht in: | Cancer 1978-07, Vol.42 (1), p.336-348 |
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| creator | Stocker, J. Thomas Ishak, Kamal G. |
| description | Thirty‐one cases of undifferentiated (embryonal) sarcoma of the liver are presented. The tumor is found predominantly in the pediatric age group, the majority of patients (51.6%) being between 6 and 10 years of age. An abdominal mass and pain are the usual presenting symptoms. Radiographic examination is nonspecific except to demonstrate a space‐occupying lesion of the liver. The tumors are large, single, usually globular and well demarcated, and have multiple cystic areas of hemorrhage, necrosis, and gelatinous degeneration. Histologic examination shows a pseudocapsule partially separating the normal liver from undifferentiated sarcomatous cells that, near the periphery of the tumor, surround entrapped hyperplastic or degenerating bile duct‐like structures. Eosinophilic globules that are PAS positive are usually found within and adjacent to tumor cells. Areas of necrosis and hemorrhage are prominent. The prognosis is poor, with a median survival of less than 1 year following diagnosis. |
| doi_str_mv | 10.1002/1097-0142(197807)42:1<336::AID-CNCR2820420151>3.0.CO;2-V |
| format | Article |
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Report of 31 cases</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Stocker, J. Thomas ; Ishak, Kamal G.</creator><creatorcontrib>Stocker, J. Thomas ; Ishak, Kamal G.</creatorcontrib><description>Thirty‐one cases of undifferentiated (embryonal) sarcoma of the liver are presented. The tumor is found predominantly in the pediatric age group, the majority of patients (51.6%) being between 6 and 10 years of age. An abdominal mass and pain are the usual presenting symptoms. Radiographic examination is nonspecific except to demonstrate a space‐occupying lesion of the liver. The tumors are large, single, usually globular and well demarcated, and have multiple cystic areas of hemorrhage, necrosis, and gelatinous degeneration. Histologic examination shows a pseudocapsule partially separating the normal liver from undifferentiated sarcomatous cells that, near the periphery of the tumor, surround entrapped hyperplastic or degenerating bile duct‐like structures. Eosinophilic globules that are PAS positive are usually found within and adjacent to tumor cells. Areas of necrosis and hemorrhage are prominent. The prognosis is poor, with a median survival of less than 1 year following diagnosis.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(197807)42:1<336::AID-CNCR2820420151>3.0.CO;2-V</identifier><identifier>PMID: 208754</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Bile Duct Neoplasms - diagnosis ; Bile Ducts, Intrahepatic - pathology ; Carcinoma, Hepatocellular - diagnosis ; Child ; Child, Preschool ; Diagnosis, Differential ; Female ; Humans ; Infant ; Infant, Newborn ; Liver Neoplasms - diagnosis ; Liver Neoplasms - pathology ; Male ; Mesenchymoma - diagnosis ; Mesenchymoma - pathology ; Neoplasm Metastasis - pathology ; Organoids - pathology ; Prognosis ; Rhabdomyosarcoma - diagnosis</subject><ispartof>Cancer, 1978-07, Vol.42 (1), p.336-348</ispartof><rights>Copyright © 1978 American Cancer Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/208754$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stocker, J. Thomas</creatorcontrib><creatorcontrib>Ishak, Kamal G.</creatorcontrib><title>Undifferentiated (embryonal) sarcoma of the liver. Report of 31 cases</title><title>Cancer</title><addtitle>Cancer</addtitle><description>Thirty‐one cases of undifferentiated (embryonal) sarcoma of the liver are presented. The tumor is found predominantly in the pediatric age group, the majority of patients (51.6%) being between 6 and 10 years of age. An abdominal mass and pain are the usual presenting symptoms. Radiographic examination is nonspecific except to demonstrate a space‐occupying lesion of the liver. The tumors are large, single, usually globular and well demarcated, and have multiple cystic areas of hemorrhage, necrosis, and gelatinous degeneration. Histologic examination shows a pseudocapsule partially separating the normal liver from undifferentiated sarcomatous cells that, near the periphery of the tumor, surround entrapped hyperplastic or degenerating bile duct‐like structures. Eosinophilic globules that are PAS positive are usually found within and adjacent to tumor cells. Areas of necrosis and hemorrhage are prominent. The prognosis is poor, with a median survival of less than 1 year following diagnosis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Bile Duct Neoplasms - diagnosis</subject><subject>Bile Ducts, Intrahepatic - pathology</subject><subject>Carcinoma, Hepatocellular - diagnosis</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Liver Neoplasms - diagnosis</subject><subject>Liver Neoplasms - pathology</subject><subject>Male</subject><subject>Mesenchymoma - diagnosis</subject><subject>Mesenchymoma - pathology</subject><subject>Neoplasm Metastasis - pathology</subject><subject>Organoids - pathology</subject><subject>Prognosis</subject><subject>Rhabdomyosarcoma - diagnosis</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkFlLw0AQgBfxqsc_8CFPUh9Sd_bIJlVEiSeIBVHxbdhuJhhJmppNlf57EyqCPs3xzQzMx9g58BFwLo6BJybkoMQQEhNzc6TEGE6ljMbji7vLMH1IH0UsuBIcNJzJER-lkxMRvqyxwe_qOhtwzuNQK_m6zXa8f-9KI7TcYpuCx0arAbt6nmVFnlNDs7awLWXBkKpps6xntjwKvG1cXdmgzoP2jYKy-KRmFDzSvG7avikhcNaT32MbuS097f_EXfZ8ffWU3ob3k5u79OI-nIvEQGid0RCRTgxXictJWyWnwuTksqnJhAaIQLoIkjyzJpMZaRDOxOSUARdDLnfZ4eruvKk_FuRbrArvqCztjOqFR6MApIqSbvDgZ3AxrSjDeVNUtlni6u0OuxX-Kkpa_lLg2MvH3iD2BnElH_sMO_nYuce_7lEix3SCAl_-EfkN81F8xw</recordid><startdate>197807</startdate><enddate>197807</enddate><creator>Stocker, J. Thomas</creator><creator>Ishak, Kamal G.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197807</creationdate><title>Undifferentiated (embryonal) sarcoma of the liver. Report of 31 cases</title><author>Stocker, J. Thomas ; Ishak, Kamal G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2971-ac7516e597049cfe5a43b27fecdb7d2511613c619fda7d3de512c78ec471c81f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Bile Duct Neoplasms - diagnosis</topic><topic>Bile Ducts, Intrahepatic - pathology</topic><topic>Carcinoma, Hepatocellular - diagnosis</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Liver Neoplasms - diagnosis</topic><topic>Liver Neoplasms - pathology</topic><topic>Male</topic><topic>Mesenchymoma - diagnosis</topic><topic>Mesenchymoma - pathology</topic><topic>Neoplasm Metastasis - pathology</topic><topic>Organoids - pathology</topic><topic>Prognosis</topic><topic>Rhabdomyosarcoma - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stocker, J. Thomas</creatorcontrib><creatorcontrib>Ishak, Kamal G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stocker, J. Thomas</au><au>Ishak, Kamal G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Undifferentiated (embryonal) sarcoma of the liver. Report of 31 cases</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1978-07</date><risdate>1978</risdate><volume>42</volume><issue>1</issue><spage>336</spage><epage>348</epage><pages>336-348</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><abstract>Thirty‐one cases of undifferentiated (embryonal) sarcoma of the liver are presented. The tumor is found predominantly in the pediatric age group, the majority of patients (51.6%) being between 6 and 10 years of age. An abdominal mass and pain are the usual presenting symptoms. Radiographic examination is nonspecific except to demonstrate a space‐occupying lesion of the liver. The tumors are large, single, usually globular and well demarcated, and have multiple cystic areas of hemorrhage, necrosis, and gelatinous degeneration. Histologic examination shows a pseudocapsule partially separating the normal liver from undifferentiated sarcomatous cells that, near the periphery of the tumor, surround entrapped hyperplastic or degenerating bile duct‐like structures. Eosinophilic globules that are PAS positive are usually found within and adjacent to tumor cells. Areas of necrosis and hemorrhage are prominent. The prognosis is poor, with a median survival of less than 1 year following diagnosis.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>208754</pmid><doi>10.1002/1097-0142(197807)42:1<336::AID-CNCR2820420151>3.0.CO;2-V</doi><tpages>13</tpages></addata></record> |
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| subjects | Adolescent Adult Bile Duct Neoplasms - diagnosis Bile Ducts, Intrahepatic - pathology Carcinoma, Hepatocellular - diagnosis Child Child, Preschool Diagnosis, Differential Female Humans Infant Infant, Newborn Liver Neoplasms - diagnosis Liver Neoplasms - pathology Male Mesenchymoma - diagnosis Mesenchymoma - pathology Neoplasm Metastasis - pathology Organoids - pathology Prognosis Rhabdomyosarcoma - diagnosis |
| title | Undifferentiated (embryonal) sarcoma of the liver. Report of 31 cases |
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