Double blind trial in the treatment of herpes simplex and herpes zoster with adenine arabinoside and idoxuridine

In a double blind trial adenine arabinoside (Vidarabine) and Idoxuridine (IDU) were tested in herpes simplex and herpes zoster infections. Adenine arabinoside covered 19 patients with HSV and 6 with HZ while IDU 19 with HSV and 6 with HZ. From the statistical analysis it was found that Vidarabine ac...

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Veröffentlicht in:	Archives of Dermatological Research 1978-01, Vol.262 (2), p.173-176
Hauptverfasser:	Theodoridis, A, Sivenas, C, Vagena, A, Capetanakis, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Child Child, Preschool Clinical Trials as Topic Double-Blind Method Herpes Simplex - drug therapy Herpes Zoster - drug therapy Humans Idoxuridine - therapeutic use Infant Infant, Newborn Middle Aged Vidarabine - therapeutic use
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Zusammenfassung:	In a double blind trial adenine arabinoside (Vidarabine) and Idoxuridine (IDU) were tested in herpes simplex and herpes zoster infections. Adenine arabinoside covered 19 patients with HSV and 6 with HZ while IDU 19 with HSV and 6 with HZ. From the statistical analysis it was found that Vidarabine acts shorter than IDU in HSV P less than 0.01, while in HZ no significant difference P less than 0.5 was found, possibly due to the small number of patients tested.
ISSN:	0340-3696 1432-069X
DOI:	10.1007/BF00455387